ArticleEuropean biophysics journal : EBJ2021
Uncertainty in protein-ligand binding constants: asymmetric confidence intervals versus standard errors.
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Article in European biophysics journal : EBJ, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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26citing papers in PubMed
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Who cites it
26 citing papers in PubMed.
- Targeting the AcrAB-TolC efflux pump by small molecules selectively addressing the outer membrane factor TolC.Frontiers in pharmacology · 2026Article
- A Browser-Based Tool for Assessing Accuracy of Isothermal Titration Calorimetry-Derived Parameters: KChembiochem : a European journal of chemical biology · 2025Article
- A Kinetic Model of Antigen-Dependent IgG Oligomerization and Complement Binding.Small science · 2025Article
- A Practical Approach to Quantitatively Assessing Equilibrium-Constant Accuracy from a Single Binding Isotherm.Precision chemistry · 2025Article
- A novel mitochondrial pyruvate carrier inhibitor drives stem cell-like memory CAR T cell generation and enhances antitumor efficacy.Molecular therapy. Oncology · 2024Article
- Complement activation by IgG subclasses is governed by their ability to oligomerize upon antigen binding.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Determination of Protein-Ligand Binding Affinities by Thermal Shift Assay.ACS pharmacology & translational science · 2024Article
- Improving the Accuracy of Permeability Data to Gain Predictive Power: Assessing Sources of Variability in Assays Using Cell Monolayers.Membranes · 2024Review
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- Substrate specificity and ecological significance of PstS homologs in phosphorus uptake in marineMicrobiology spectrum · 2024Article
- Interaction of Hoechst 33342 with POPC Membranes at Different pH Values.Molecules (Basel, Switzerland) · 2023Article
- Efflux Pump-Binding 4(3-Aminocyclobutyl)Pyrimidin-2-Amines Are Colloidal Aggregators.Biomolecules · 2023Article
- PLBD: protein-ligand binding database of thermodynamic and kinetic intrinsic parameters.Database : the journal of biological databases and curation · 2023Article
- Interaction of a Homologous Series of Amphiphiles with P-glycoprotein in a Membrane Environment-Contributions of Polar and Non-Polar Interactions.Pharmaceutics · 2023Article
- Characterization of ATG8-Family Interactors by Isothermal Titration Calorimetry.Methods in molecular biology (Clifton, N.J.) · 2023Article
- Picomolar fluorescent probes for compound affinity determination to carbonic anhydrase IX expressed in live cancer cells.Scientific reports · 2022Article
- Repositioning small molecule drugs as allosteric inhibitors of the BFT-3 toxin from enterotoxigenic Bacteroides fragilis.Protein science : a publication of the Protein Society · 2022Article
- Cosolvent Sites-Based Discovery ofJournal of medicinal chemistry · 2022Article
- Article
- Interactions between Rhodamine Dyes and Model Membrane Systems-Insights from Molecular Dynamics Simulations.Molecules (Basel, Switzerland) · 2022Article
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Authors and funding
13 authors.
Vaida PaketurytėDepartment of Biothermodynamics and Drug Design, Institute of Biotechnology, Life Sciences Center, Vilnius University, Saulėtekio 7, 10257, Vilnius, Lithuania.ORCID https://orcid.org/0000-0003-0919-7826
Vytautas PetrauskasDepartment of Biothermodynamics and Drug Design, Institute of Biotechnology, Life Sciences Center, Vilnius University, Saulėtekio 7, 10257, Vilnius, Lithuania.ORCID https://orcid.org/0000-0001-7983-4128
Asta ZubrienėDepartment of Biothermodynamics and Drug Design, Institute of Biotechnology, Life Sciences Center, Vilnius University, Saulėtekio 7, 10257, Vilnius, Lithuania.ORCID https://orcid.org/0000-0001-5996-1883
Olga AbianInstitute of Biocomputation and Physics of Complex Systems (BIFI), Joint Units IQFR-CSIC-BIFI, and GBsC-CSIC-BIFI, Universidad de Zaragoza, Zaragoza, Spain.ORCID https://orcid.org/0000-0001-5664-1729
Margarida BastosDepartment of Chemistry and Biochemistry, Faculty of Sciences, CIQ-UP, University of Porto, Porto, Portugal. mbastos@fc.up.pt.ORCID https://orcid.org/0000-0001-7464-3568
Wen-Yih ChenDepartment of Chemical and Materials Engineering, National Central University, Taoyüan, Taiwan.ORCID https://orcid.org/0000-0002-9930-7605
Maria João MorenoChemistry Department, Faculty of Sciences and Technology, Coimbra Chemistry Center, University of Coimbra, 3004-535, Coimbra, Portugal.ORCID https://orcid.org/0000-0003-3076-9905
Georg KrainerYusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, UK.ORCID https://orcid.org/0000-0002-9626-7636
Vaida LinkuvienėDepartment of Biothermodynamics and Drug Design, Institute of Biotechnology, Life Sciences Center, Vilnius University, Saulėtekio 7, 10257, Vilnius, Lithuania.ORCID https://orcid.org/0000-0003-2075-8145
Arthur SedivyProtein Technologies, Vienna Biocenter Core Facilities GmbH, Vienna, Austria. arthur.sedivy@vbcf.ac.at.ORCID https://orcid.org/0000-0002-5729-9790
Adrian Velazquez-CampoyInstitute of Biocomputation and Physics of Complex Systems (BIFI), Joint Units IQFR-CSIC-BIFI, and GBsC-CSIC-BIFI, Universidad de Zaragoza, Zaragoza, Spain. adrianvc@unizar.es.ORCID https://orcid.org/0000-0001-5702-4538
Mark A WilliamsDepartment of Biological Sciences, Institute for Structural and Molecular Biology, Birkbeck, University of London, London, UK. ma.williams@bbk.ac.uk.ORCID https://orcid.org/0000-0002-1645-2189
Daumantas MatulisDepartment of Biothermodynamics and Drug Design, Institute of Biotechnology, Life Sciences Center, Vilnius University, Saulėtekio 7, 10257, Vilnius, Lithuania. daumantas.matulis@bti.vu.lt.ORCID https://orcid.org/0000-0002-6178-6276
Funding
Fundação para a Ciência e Tecnologia (FCT) UID/QUI/0081/2013Lietuvos Mokslo Taryba S-LLT-20-2
Abstract
Equilibrium binding constants (K
Indexed as
UncertaintyCalorimetryConfidence IntervalsLigandsProtein BindingThermodynamicsLigandsBinding constantConfidence intervalsDissociation constantIsothermal titration calorimetryLog-normal distributionStandard error
Identifiers
PMID
33837826What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.