Evidence map›Paper›PMID 33837819›Full record

ArticleWorld journal of urology2021

Global Greenlight Group: largest international Greenlight experience for benign prostatic hyperplasia to assess efficacy and safety.

Kyle W Law, Côme Tholomier, David-Dan Nguyen, Iman Sadri, Félix Couture, Ahmed S Zakaria, David Bouhadana, Franck Bruyère, Hannes Cash, Maximilian Reimann and 9 more

Abstract read
PubMed Publisher
In one paragraph

Article in World journal of urology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
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  4. GreenLight laser prostatectomy: Are outcomes sustainable after a decade of surgery? A single-center experience with up to 15 years' followup.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Kyle W LawFaculty of Medicine, McGill University, Montreal, QC, Canada.ORCID http://orcid.org/0000-0002-7900-8800
Côme TholomierDepartment of Surgery, Division of Urology, McGill University, Montreal, QC, Canada.
David-Dan NguyenFaculty of Medicine, McGill University, Montreal, QC, Canada.
Iman SadriFaculty of Medicine, McGill University, Montreal, QC, Canada.
Félix CoutureDepartment of Surgery, Division of Urology, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, QC, Canada.
Ahmed S ZakariaDepartment of Urology, University of Montreal Hospital Center CHUM, Montreal, QC, Canada.
David BouhadanaFaculty of Medicine, McGill University, Montreal, QC, Canada.
Franck BruyèreDepartment of Oncology and Urology, Centre Hospitalier Universitaire de Tours, Centre-Val de Loire, France.
Hannes CashDepartment of Urology, Charité-Universitaetsmedizin Berlin, Berlin, Germany.
Maximilian ReimannDepartment of Urology, Charité-Universitaetsmedizin Berlin, Berlin, Germany.
Luca CindoloDepartment of Urology, Hesperia Hospital, Cure Group, Modena, Italy.
Giovanni FerrariDepartment of Urology, Hesperia Hospital, Cure Group, Modena, Italy.
Carlos Vasquez-LastraDepartment of Urology, ABC Medical Center, Mexico City, Mexico.
Tiago J Borelli-BovoBorelli Urologia, Ribeirão Presto, Brazil.
Edgardo F BecherCentro de Urologia, CDU, Buenos Aires, Argentina.
Vincent MisraiDepartment of Urology, Clinique Pasteur, Toulouse, Midi-Pyrenees, France.
Dean EltermanDivision of Urology, Department of Surgery, University. Health Network, University of Toronto, Toronto, ON, Canada.
Naeem BhojaniDepartment of Urology, University of Montreal Hospital Center CHUM, Montreal, QC, Canada.
Kevin C ZornDepartment of Urology, University of Montreal Hospital Center CHUM, Montreal, QC, Canada. zorn.chumurology@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionGreenlight photo-selective vaporization of the prostate (GL-PVP) has gained international acceptance as a safe and effective alternative procedure for the treatment of benign prostatic hyperplasia (BPH), especially in anticoagulated men. This descriptive analysis aims to characterize the current state of GL-PVP, pooling data from international centers.

methodsData from 3627 patients who underwent GL-PVP with the XPS-180 W system in seven international centers performed by eight expert surgeons between 2011 and 2019 were retrospectively analyzed. Demographic, perioperative, and postoperative data were collected, including IPSS, QoL, Qmax, PVR, and PSA, and complications.

resultsAt baseline, median age, prostate volume, PSA, and IPSS were 70 years (interquartile range 64-77), 64 (47-90), 3.1 ng/mL (1.8-6), and 22 (19-27), respectively. Median lasing and operative time were 34 (23-48) and 62 min (46-85), respectively. Median energy use was 250.0 kJ (168.4-367.9), with 92.6% of procedures being completed with one laser fiber. In 60.1% of cases, catheter was removed on postoperative day 1 with median length of 2 days. All-cause mortality within 30 days was 0.3%. Median PSA reduction at 3 months and 60 months compared to baseline was 43.9 and 46.4%, respectively (p < 0.001). All functional outcomes (IPSS, QoL, Qmax, and PVR) were significantly improved across study period when compared to baseline (p < 0.001). For those men with longer follow-up available, the observed surgical BPH retreatment rate was 1.5%

conclusionUsing the largest multi-user, international database of GL-PVP, Greenlight XPS laser treatment in experienced hands is a safe, effective, and durable BPH treatment option.

Indexed as

Laser TherapyAgedHumansMaleMiddle AgedProstatectomyProstatic HyperplasiaRetrospective StudiesTreatment OutcomeVolatilizationBPEBPHGreenlight PVPPhotovaporizationProstate

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.