Evidence map›Paper›PMID 33837727›Full record

ArticleThe Journal of biological chemistry

Decrypting the chaperone code.

Andrew W Truman, Dimitra Bourboulia, Mehdi Mollapour

Abstract read
In one paragraph

Article in The Journal of biological chemistry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Ligand-driven modulation of chaperone-cochaperone networks shapes proteostasis outcomes.Protein science : a publication of the Protein Society · 2026
    Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. HSPA6 and its role in cancers and other diseases.Molecular biology reports · 2022
    Review
  13. Article
  14. Article
  15. Article
  16. A novel and unique ATP hydrolysis to AMP by a human Hsp70 Binding immunoglobin protein (BiP).Protein science : a publication of the Protein Society · 2022
    Article
  17. Article
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Andrew W TrumanDepartment of Biological Sciences, University of North Carolina at Charlotte, Charlotte, North Carolina, USA. Electronic address: atruman1@uncc.edu.
Dimitra BourbouliaDepartment of Urology, SUNY Upstate Medical University, Syracuse, New York, USA; Department of Biochemistry and Molecular Biology, SUNY Upstate Medical University, Syracuse, New York, USA; Upstate Cancer Center, SUNY Upstate Medical University, Syracuse, New York, USA. Electronic address: bourmpod@upstate.edu.
Mehdi MollapourDepartment of Urology, SUNY Upstate Medical University, Syracuse, New York, USA; Department of Biochemistry and Molecular Biology, SUNY Upstate Medical University, Syracuse, New York, USA; Upstate Cancer Center, SUNY Upstate Medical University, Syracuse, New York, USA. Electronic address: mollapom@upstate.edu.

Funding

Regulatory mechanisms of the Hsp90 chaperone machinery.R35GM139584 · NIGMS · UPSTATE MEDICAL UNIVERSITY · PI MOLLAPOUR, MEHDI · 2021 to 2025
$2.2M
Understanding the reciprocal regulation between Hsp70 and the DNA damage response.R01GM139885 · NIGMS · UNIVERSITY OF NORTH CAROLINA CHARLOTTE · PI TRUMAN, ANDREW WILLIAM · 2021 to 2024
$1.4M
Crosstalk between post-translational regulations of the FNIP co-chaperones and their impact on Hsp90 chaperone function and drug bindingR01GM124256 · NIGMS · UPSTATE MEDICAL UNIVERSITY · PI MOLLAPOUR, MEHDI · 2017 to 2020
$1.3M
Regulation of the extracellular HSP90 chaperone machineryR01GM139932 · NIGMS · UPSTATE MEDICAL UNIVERSITY · PI BOURBOULIA, DIMITRA · 2021 to 2024
$1.3M
Understanding ER chaperone-mediated RNR regulationR15GM139059 · NIGMS · UNIVERSITY OF NORTH CAROLINA CHARLOTTE · PI TRUMAN, ANDREW WILLIAM · 2020 to 2020
$440k
NIGMS NIH HHS R01 GM124256NIGMS NIH HHS R01 GM139885NIGMS NIH HHS R01 GM139932NIGMS NIH HHS R15 GM139059NIGMS NIH HHS R35 GM139584
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsHeat Shock Transcription FactorsHSP70 Heat-Shock ProteinsHSP90 Heat-Shock ProteinsHumansHeat Shock Transcription FactorsHSF1 protein, humanHSP70 Heat-Shock ProteinsHSP90 Heat-Shock ProteinsTRAP1 protein, humanChaperone codeCo-chaperonesExtracellular chaperonesHSF1Hsp70Hsp90Post-translational modificationsTRAP1

Identifiers

PMID33837727
PMCPMC7949055

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.