Evidence map›Paper›PMID 33837537›Full record

ArticleJournal of the American Geriatrics Society2021

Trends in antipsychotic prescribing among long-term care residents receiving hospice care.

Lauren B Gerlach, Shekinah Fashaw, Julie Strominger, Jessica Ogarek, Andrew R Zullo, Lori A Daiello, Joan Teno, Theresa I Shireman, Julie P W Bynum

Open access · bronzeAbstract read
In one paragraph

Article in Journal of the American Geriatrics Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
5.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Lauren B GerlachDepartment of Psychiatry, University of Michigan, Ann Arbor, Michigan, USA.ORCID 0000-0003-1943-0150
Shekinah FashawCenter for Gerontology and Healthcare Research, Brown University, Providence, Rhode Island, USA.ORCID 0000-0002-0077-5047
Julie StromingerCenter for Clinical Management Research, VA Ann Arbor Healthcare System, Ann Arbor, Michigan, USA.
Jessica OgarekCenter for Gerontology and Healthcare Research, Brown University, Providence, Rhode Island, USA.
Andrew R ZulloCenter for Gerontology and Healthcare Research, Brown University, Providence, Rhode Island, USA.ORCID 0000-0003-1673-4570
Lori A DaielloCenter for Gerontology and Healthcare Research, Brown University, Providence, Rhode Island, USA.
Joan TenoDepartment of Internal Medicine, Oregon Health and Sciences University, Portland, Oregon, USA.
Theresa I ShiremanCenter for Gerontology and Healthcare Research, Brown University, Providence, Rhode Island, USA.
Julie P W BynumInstitute for Healthcare Policy and Innovation, University of Michigan, Ann Arbor, Michigan, USA.
Brown University · USUniversity of Michigan · USOregon Health & Science University · USVA Ann Arbor Healthcare System · US

Funding

VARIATIONS IN LIFE'S FINAL CHAPTERP01AG027296 · NIA · BROWN UNIVERSITY · PI AMAL N. TRIVEDI · 2007 to 2026
$38.9M
Medicating distress: Use of psychotropic medications among patients with dementia receiving hospice careK23AG066864 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GERLACH, LAUREN BETH · 2021 to 2025
$1.0M
Use of Psychotropic Medications Among Older Adults Receiving Hospice CareR03AG060073 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GERLACH, LAUREN BETH · 2018 to 2019
$234k
NIA NIH HHS K23 AG066864NIA NIH HHS P01 AG027296NIA NIH HHS P01AG027296NIA NIH HHS R03 AG060073NIA NIH HHS R03AG060073
6 · The paper itself

Abstract

importanceThe Centers for Medicare & Medicaid Services' (CMS) National Partnership to Improve Dementia Care in Nursing Homes ("CMS National Partnership") focuses on reducing antipsychotic prescribing to long-term care residents. Hospice enrollment is not an exclusionary condition for the antipsychotic quality measure reported by CMS. It is unclear how prescribing in hospice may have been impacted by the initiative.

objectiveEstimate the association of the CMS National Partnership with trends in antipsychotic prescribing among long-term care residents in hospice.

designInterrupted time-series analysis of a 100% Minimum Data Set sample with linked hospice claims from 2011 to 2017.

settingLong-term care nursing facilities.

participantsOlder adults ≥65 residing in long-term care (n = 3,741,379) and limited to those enrolled in hospice (n = 821,610). MAIN OUTCOME: Quarterly prevalence of antipsychotic and other psychotropic (antianxiety, hypnotic, antidepressant) use among long-term care residents; overall and among residents with dementia, stratified by hospice enrollment.

resultsFrom 2011 to 2017, parallel declines in antipsychotic prescribing were observed among long-term care residents enrolled and not enrolled in hospice (hospice: decline from 26.8% to 18.7%; non-hospice: decline from 23.0% to 14.4%). Following the 2012 CMS National Partnership, quarterly rates of antipsychotic prescribing declined significantly for both residents enrolled and not enrolled in hospice care. Declines in antipsychotic prescribing were greater for residents with dementia, with similar rates among residents enrolled and not enrolled in hospice. Among residents with dementia enrolled in hospice, use of other psychotropic medication classes including antianxiety, antidepressant, and hypnotic use remained relatively stable over time. CONCLUSIONS AND RELEVANCE: Declines in antipsychotic prescribing during the CMS National Partnership occurred among long-term care residents in hospice, where use may be deemed clinically appropriate. Nursing homes are an important location for the provision of dementia end-of-life care and the drivers of potentially unintended reductions in antipsychotic use merits further investigation.

Indexed as

AgedAged, 80 and overAntipsychotic AgentsCenters for Medicare and Medicaid Services, U.S.DementiaFemaleHospice CareHumansInappropriate PrescribingInterrupted Time Series AnalysisLong-Term CareMaleQuality ImprovementUnited StatesAntipsychotic Agentsantipsychotic medicationhospicenursing home

Identifiers

PMID33837537
PMCPMC8373635
OpenAlexW3139890494

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.