Evidence map›Paper›PMID 33837499›Full record

ArticleCancer causes & control : CCC2021

Post-diagnostic coffee and tea consumption and risk of prostate cancer progression by smoking history.

Crystal S Langlais, June M Chan, Stacey A Kenfield, Janet E Cowan, Rebecca E Graff, Jeanette M Broering, Peter Carroll, Erin L Van Blarigan

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer causes & control : CCC, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Smoking and the risk of prostate cancer: a review of risk and disease progression.Genes and environment : the official journal of the Japanese Environmental Mutagen Society · 2025
    Review
  3. Observational
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Crystal S LanglaisDepartment of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, USA. crystal.langlais@ucsf.edu.ORCID http://orcid.org/0000-0001-5654-5542
June M ChanDepartment of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, USA.
Stacey A KenfieldDepartment of Urology, University of California, San Francisco, San Francisco, CA, USA.
Janet E CowanDepartment of Urology, University of California, San Francisco, San Francisco, CA, USA.
Rebecca E GraffDepartment of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, USA.
Jeanette M BroeringDepartment of Urology, University of California, San Francisco, San Francisco, CA, USA.
Peter CarrollDepartment of Urology, University of California, San Francisco, San Francisco, CA, USA.
Erin L Van BlariganDepartment of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, USA.
University of California, San Francisco · US

Funding

Diet After Colorectal Cancer : Observational Studies to Behavioral InterventionsK07CA197077 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI VAN BLARIGAN, ERIN LYNN · 2016 to 2020
$885k
Impact of Modifiable Diet and Lifestyle Factors on Prostate Cancer ProgressionF31CA247093 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LANGLAIS, CRYSTAL · 2020 to 2021
$54k
NCI NIH HHS F31 CA247093NCI NIH HHS K07 CA197077NCI NIH HHS K07CA197077U.S. Department of Defense W81XWH-04-1-0850U.S. Department of Defense W81XWH-13-2-0074
6 · The paper itself

Abstract

purposePost-diagnostic coffee and tea consumption and prostate cancer progression is understudied.

methodsWe examined 1,557 men from the Cancer of the Prostate Strategic Urologic Research Endeavor who completed a food frequency questionnaire a median of 28 months post-diagnosis. We estimated associations between post-diagnostic coffee (total, caffeinated, decaffeinated) and tea (total, non-herbal, herbal) and risk of prostate cancer progression (recurrence, secondary treatment, bone metastases, or prostate cancer death) using Cox proportional hazards regression. We also examined whether smoking (current, former, never) modified these associations.

resultsWe observed 167 progression events (median follow-up 9 years). Higher coffee intake was associated with higher risk of progression among current smokers (n = 95). The hazard ratio (HR) [95% confidence interval (CI)] for 5 vs 0 cups/day of coffee was 0.5 (CI 0.2, 1.7) among never smokers, but 4.5 (CI 1.1, 19.4) among current smokers (p-interaction: 0.001). There was no association between total coffee intake and prostate cancer progression among never and former smokers. However, we observed an inverse association between decaffeinated coffee (cups/days) and risk of prostate cancer progression in these men (HR

conclusionAmong non-smoking men diagnosed with localized prostate cancer, moderate coffee and tea consumption was not associated with risk of cancer progression. However, post-diagnostic coffee intake was associated with increased risk of progression among current smokers.

Indexed as

CoffeeTeaAdultAgedCancer SurvivorsDisease ProgressionFollow-Up StudiesHumansMaleMiddle AgedNeoplasm Recurrence, LocalNutrition SurveysProportional Hazards ModelsProstatic NeoplasmsRisk FactorsSmokingCoffeeTeaCancer recurrenceCoffeePost-diagnostic lifestyleSurvivorshipTea

Identifiers

PMID33837499
PMCPMC8189293
OpenAlexW3146728053

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.