Evidence map›Paper›PMID 33837282›Full record

ArticleScientific reports2021

The risk of pulmonary tuberculosis after traumatic brain injury.

Hsin-Yueh Liu, Kuang-Ming Liao, Fu-Wen Liang, Yi-Chieh Hung, Jhi-Joung Wang, Te-Chun Shen, Chung-Han Ho

Abstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Integrative genomic and clinical analysis of carbapenem-resistant and susceptibleFrontiers in cellular and infection microbiology · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hsin-Yueh Liu *Department of Internal Medicine, Chi Mei Medical Center, Chiali, Taiwan.
Kuang-Ming Liao *Department of Internal Medicine, Chi Mei Medical Center, Chiali, Taiwan.
Fu-Wen LiangDepartment of Public Health, College of Health Sciences, Kaohsiung Medical University, Kaohsiung, Taiwan.
Yi-Chieh HungDepartment of Neurosurgery, Department of Surgery, Chi-Mei Medical Center, Tainan, Taiwan.
Jhi-Joung WangDepartment of Medical Research, Chi Mei Medical Center, No 901, Zhonghua Road, Yongkang District, Tainan City 710, Taiwan.
Te-Chun ShenSchool of Medicine, China Medical University, Taichung, Taiwan. chestshen@gmail.com.
Chung-Han HoDepartment of Medical Research, Chi Mei Medical Center, No 901, Zhonghua Road, Yongkang District, Tainan City 710, Taiwan. ho.c.hank@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

After traumatic brain injury (TBI), an inflammatory response in the brain might affect the immune system. The risk of pulmonary infection reportedly increases in patients with TBI. We aimed to evaluate the risk of tuberculosis (TB) in patients with TBI in Taiwan. All participants were selected from the intensive care unit (ICU). Patients with TBI were defined as patients in ICU with intracranial injury, and comparison cohort were patients in ICU without TBI diagnosis. There was a significant difference in TB risk between the patients with TBI and the comparison cohort according to age and the Charlson's comorbidity index (CCI) score. Thus, we divided patients based on CCI into three groups for further analysis: mild (CCI = 0), moderate (CCI = 1/2), severe (CCI > 2). Mild-CCI group had a lower TB incidence rate (0.74%) and longer time to TB development (median: 2.43) than the other two groups. Moderate-CCI group had 1.52-fold increased risk of TB infection (p < 0.0001) compared with mild-CCI group. In the severe-CCI group, patients aged ≥ 80 years had 1.91-fold risk of TB compared with mild-CCI group (p = 0.0481). Severe-CCI group had significantly higher mortality than the mild-CCI group (p = 0.0366). Patients with TBI and more comorbidities had higher risk of TB infection with higher mortality rate.

Indexed as

Mycobacterium tuberculosisAdultAgedAged, 80 and overBrain Injuries, TraumaticCohort StudiesComorbidityFemaleHumansIncidenceIntensive Care UnitsMaleMiddle AgedPatient AdmissionRisk FactorsSeverity of Illness Index

Identifiers

PMID33837282
PMCPMC8035358

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.