ArticleScientific reports2021
Motor and sensory features successfully decode autism spectrum disorder and combine with the original RDoC framework to boost diagnostic classification.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Gaze and social functioning associations in autism spectrum disorder: A systematic review and meta-analysis.Autism research : official journal of the International Society for Autism Research · 2022Pooled it
- Specific tractography differences in autism compared to developmental coordination disorder.Scientific reports · 2022Trial
- Syngap1 Synchronizes Relative Neuronal Maturation Across Cortical Areas to Organize Distributed Functional Networks.bioRxiv : the preprint server for biology · 2026Article
- SHAP-based explainable AI framework for autism severity classification using 3D motor biomarkers.Frontiers in psychiatry · 2026Article
- Motor Control Adherence to the Two-thirds Power Law Differs in Autistic Development.Journal of autism and developmental disorders · 2025Article
- Sensory-movement underpinnings of lifelong neurodivergence: getting a grip on autism.Frontiers in integrative neuroscience · 2025Article
- Motor Signature Differences Between Autism Spectrum Disorder and Developmental Coordination Disorder, and Their Neural Mechanisms.Journal of autism and developmental disorders · 2025Article
- Cooking for disability: a pilot study on nutritional interventions for mental health support in adults with autism spectrum disorder.Frontiers in psychiatry · 2025Article
- Deliberate synchronization of speech and gesture: Effects of neurodiversity and development.Language and cognition · 2024Article
- Auditory feedback decreases timing variability for discontinuous and continuous motor tasks in autistic adults.Frontiers in integrative neuroscience · 2024Article
- Relationships between Affect Recognition, Empathy, Alexithymia, and Co-Occurring Conditions in Autism.Brain sciences · 2023Article
- A brain structural connectivity biomarker for autism spectrum disorder diagnosis in early childhood.Psychoradiology · 2023Article
- The whole-body motor skills of children with autism spectrum disorder taking goal-directed actions in virtual reality.Frontiers in psychology · 2023Article
- Motor performance, praxis, and social skills in autism spectrum disorder and developmental coordination disorder.Autism research : official journal of the International Society for Autism Research · 2022Article
- Sensory Modulation in Children with Developmental Coordination Disorder Compared to Autism Spectrum Disorder and Typically Developing Children.Brain sciences · 2022Article
- Perspective: Acknowledging complexity to advance the understanding of developmental coordination disorder.Frontiers in human neuroscience · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Sensory processing and motor coordination atypicalities are not commonly identified as primary characteristics of autism spectrum disorder (ASD), nor are they well captured in the NIMH's original Research Domain Criteria (RDoC) framework. Here, motor and sensory features performed similarly to RDoC features in support vector classification of 30 ASD youth against 33 typically developing controls. Combining sensory with RDoC features boosted classification performance, achieving a Matthews Correlation Coefficient (MCC) of 0.949 and balanced accuracy (BAcc) of 0.971 (p = 0.00020, calculated against a permuted null distribution). Sensory features alone successfully classified ASD (MCC = 0.565, BAcc = 0.773, p = 0.0222) against a clinically relevant control group of 26 youth with Developmental Coordination Disorder (DCD) and were in fact required to decode against DCD above chance. These findings highlight the importance of sensory and motor features to the ASD phenotype and their relevance to the RDoC framework.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.