Evidence map›Paper›PMID 33837034›Full record

ArticleBMJ case reports2021

Giant parathyroid adenoma and challenges with preoperative differentiation from malignancy.

Grace Wong, Andrew Ghabbour, Farzad Borumandi

Open access · greenAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Grace WongDepartment of Oral and Maxillofacial Surgery, University Hospitals Sussex NHS Foundation Trust, St Richards Hospital, Chichester, UK.
Andrew GhabbourDepartment of Diabetes and Endocrinology, University Hospitals Sussex NHS Foundation Trust, Worthing Hospital, Worthing, UK.
Farzad BorumandiDepartment of Oral and Maxillofacial Surgery, University Hospitals Sussex NHS Foundation Trust, St Richards Hospital, Chichester and Worthing Hospital, Worthing, UK farzad.borumandi@nhs.net.
St Richard's Hospital · GBWorthing Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Giant parathyroid adenomas are rare and underreported benign tumours of parathyroid gland. Preoperative differentiation between giant parathyroid adenoma (GPA) and parathyroid carcinoma can be challenging, as they both may present as a large parathyroid tumour with hyperparathyroidism. Very few GPAs had been described in the literature, with only 60 cases including our present case. We report a case of GPA and the preoperative diagnostic challenges we faced in differential diagnosis of a potential parathyroid malignancy. As a parathyroid malignancy could not be excluded preoperatively the parathyroid tumour was excised en bloc with surrounding thyroid lobe. The histology was contributory to exclude parathyroid malignancy confirming a benign GPA.

Indexed as

AdenomaHyperparathyroidismParathyroid NeoplasmsHumansParathyroidectomyParathyroid Glandscalcium and boneendocrine cancerhead and neck surgery

Identifiers

PMID33837034
PMCPMC8043017
OpenAlexW3147322645

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.