Evidence map›Paper›PMID 33836578›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

Expansions of adaptive-like NK cells with a tissue-resident phenotype in human lung and blood.

Demi Brownlie, Marlena Scharenberg, Jeff E Mold, Joanna Hård, Eliisa Kekäläinen, Marcus Buggert, Son Nguyen, Jennifer N Wilson, Mamdoh Al-Ameri, Hans-Gustaf Ljunggren and 2 more

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed
5.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 83 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Resident CD49aScience advances · 2026
    Article
  9. Article
  10. Review
  11. Article
  12. Natural killer cell-based immunotherapy for cancer.Journal of immunology (Baltimore, Md. : 1950) · 2025
    Review
  13. Review
  14. Article
  15. CITE-Seq Analysis Reveals a Differential Natural Killer CellInternational journal of molecular sciences · 2025
    Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 3 countries.

Demi BrownlieCenter for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, 14152 Stockholm, Sweden.ORCID 0000-0001-5932-6425
Marlena ScharenbergCenter for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, 14152 Stockholm, Sweden.ORCID 0000-0002-7659-7216
Jeff E MoldDepartment of Cell and Molecular Biology, Karolinska Institutet, 171 77 Stockholm, Sweden.ORCID 0000-0003-2195-2978
Joanna HårdDepartment of Cell and Molecular Biology, Karolinska Institutet, 171 77 Stockholm, Sweden.ORCID 0000-0003-4575-5629
Eliisa KekäläinenTranslational Immunology Research Program, University of Helsinki, 00014 Helsinki, Finland.ORCID 0000-0001-6045-108X
Marcus BuggertCenter for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, 14152 Stockholm, Sweden.ORCID 0000-0003-0633-1719
Son NguyenDepartment of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
Jennifer N WilsonCenter for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, 14152 Stockholm, Sweden.
Mamdoh Al-AmeriThoracic Surgery, Department of Molecular Medicine and Surgery, Karolinska University Hospital, Karolinska Institutet, 171 76 Stockholm, Sweden.
Hans-Gustaf LjunggrenCenter for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, 14152 Stockholm, Sweden.ORCID 0000-0003-0908-7387
Nicole MarquardtCenter for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, 14152 Stockholm, Sweden; nicole.marquardt@ki.se.ORCID 0000-0003-3186-4752
Jakob MichaëlssonCenter for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, 14152 Stockholm, Sweden.
Karolinska Institutet · SEKarolinska University Hospital · SEUniversity of Helsinki · FIUniversity of Pennsylvania · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human adaptive-like "memory" CD56

Indexed as

Adaptation, PhysiologicalFlow CytometryHumansImmunophenotypingIntegrin alpha1Killer Cells, NaturalLungLung NeoplasmsIntegrin alpha1adaptivelungmemoryNK cellstissue-resident

Identifiers

PMID33836578
PMCPMC7980282
OpenAlexW3134391811

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.