ArticleNeuroImage2021
Gray matter volume in left intraparietal sulcus predicts longitudinal gains in subtraction skill in elementary school.
Article in NeuroImage, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed, 14 citations in OpenAlex.
- Experience-dependent cortical plasticity in response to formal schooling: Effects on networks for reading and mathematics.Developmental cognitive neuroscience · 2026Article
- Glutamatergic signaling underlies brain structural organization for mathematical and reading abilities in children.Nature communications · 2026Article
- Contextualizing Socioeconomic Status Effects on Adolescent Brain Structure and Cognitive Skills: Evidence From the ABCD Study.Developmental science · 2026Article
- The association between longitudinal changes in inter-hemispheric IPS functional connectivity and math gains depends on children's age and task requirements.Developmental cognitive neuroscience · 2026Article
- Lesion-symptom mapping reveals differential relationships between language and precise versus approximate numeracy.Cortex; a journal devoted to the study of the nervous system and behavior · 2025Article
- Separating neurocognitive mechanisms of maintenance and compensation to support financial ability in middle-aged and older adults: The role of language and the inferior frontal gyrus.Archives of gerontology and geriatrics · 2025Article
- Structural and transcriptional signatures of arithmetic abilities in children.NPJ science of learning · 2024Article
- Neuroanatomical, transcriptomic, and molecular correlates of math ability and their prognostic value for predicting learning outcomes.Science advances · 2024Article
- Arithmetic skills are associated with left fronto-temporal gray matter volume in 536 children and adolescents.NPJ science of learning · 2023Article
- Neurocognitive mechanisms underlying multiplication and subtraction performance in adults and skill development in children: A scoping review.Current opinion in behavioral sciences · 2022Article
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Although behavioral studies show large improvements in arithmetic skills in elementary school, we do not know how brain structure supports math gains in typically developing children. While some correlational studies have investigated the concurrent association between math performance and brain structure, such as gray matter volume (GMV), longitudinal studies are needed to infer if there is a causal relation. Although discrepancies in the literature on the relation between GMV and math performance have been attributed to the different demands on quantity vs. retrieval mechanisms, no study has experimentally tested this assumption. We defined regions of interests (ROIs) associated with quantity representations in the bilateral intraparietal sulcus (IPS) and associated with the storage of arithmetic facts in long-term memory in the left middle and superior temporal gyri (MTG/STG), and studied associations between GMV in these ROIs and children's performance on operations having greater demands on quantity vs. retrieval mechanisms, namely subtraction vs. multiplication. The aims of this study were threefold: First, to study concurrent associations between GMV and math performance, second, to investigate the role of GMV at the first time-point (T1) in predicting longitudinal gains in math skill to the second time-point (T2), and third, to study whether changes in GMV over time were associated with gains in math skill. Results showed no concurrent association between GMV in IPS and math performance, but a concurrent association between GMV in left MTG/STG and multiplication skill at T1. This association showed that the higher the GMV in this ROI, the higher the children's multiplication skill. Results also revealed that GMV in left IPS and left MTG/STG predicted longitudinal gains in subtraction skill only for younger children (approximately 10 years old). Whereas higher levels of GMV in left IPS at T1 predicted larger subtraction gains, higher levels of GMV in left MTG/STG predicted smaller gains. GMV in left MTG/STG did not predict longitudinal gains in multiplication skill. No significant association was found between changes in GMV over time and longitudinal gains in math. Our findings support the early importance of brain structure in the IPS for mathematical skills that rely on quantity mechanisms.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.