ArticleThe Journal of pediatrics2021
Health-Related Quality of Life from Adolescence to Adulthood Following Extremely Preterm Birth.
Article in The Journal of pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 30 citations in OpenAlex.
- Cognitive Training for Visuospatial Processing in Children Aged 5½ to 6 Years Born Very Preterm With Working Memory Dysfunction: A Randomized Clinical Trial.JAMA network open · 2023Trial
- Effect of Early High-Dose Recombinant Human Erythropoietin on Behavior and Quality of Life in Children Aged 5 Years Born Very Preterm: Secondary Analysis of a Randomized Clinical Trial.JAMA network open · 2022Trial
- Defining the mechanisms of neuroinflammation and antepartum neuroprotection in human neural progenitor cells and microglia.AJOG global reports · 2026Article
- Tracking visual outcomes - Follow-up on patients born preterm with childhood-onset visual impairment.Acta ophthalmologica · 2025Article
- Health-related quality of life in children with bronchopulmonary dysplasia: examining agreement between child self-report and parent proxy.European journal of pediatrics · 2024Article
- Health-related quality of life at age 10 years in children born extremely preterm.Journal of perinatology : official journal of the California Perinatal Association · 2024Article
- Psychometric Performance of Generic Childhood Multi-Attribute Utility Instruments in Preterm and Low Birthweight Populations: A Systematic Review.Children (Basel, Switzerland) · 2023Review
- Child and family factors associated with positive outcomes among youth born extremely preterm.Pediatric research · 2023Article
- Extremely premature birth bioethical decision-making supported by dialogics and pragmatism.BMC medical ethics · 2023Article
- Reduced health-related quality of life in children born extremely preterm in 2006 compared with 1995: the EPICure Studies.Archives of disease in childhood. Fetal and neonatal edition · 2022Article
- Neurodevelopmental disorders and somatic diagnoses in a national cohort of children born before 24 weeks of gestation.Acta paediatrica (Oslo, Norway : 1992) · 2022Article
- Molding influences of prematurity: Interviews with adults born preterm.Early human development · 2022Article
- Neurobehavioral Phenotype and Dysexecutive Syndrome of Preterm Children: Comorbidity or Trigger? An Update.Children (Basel, Switzerland) · 2022Review
- Extreme prematurity: Risk and resiliency.Current problems in pediatric and adolescent health care · 2022Review
- Changes in Self-reported Quality of Life as Survivors of Extremely Preterm Birth Enter Adulthood.The Journal of pediatrics · 2021Article
- A randomized EPIREMED protocol study on the long-term visuo spatial effects of very preterm children with a working memory deficit.BMC pediatrics · 2021Article
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Authors and funding
5 authors at 4 institutions in 2 countries.
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Abstract
objectiveTo examine self-reported and parent-reported health-related quality of life (HRQL) in adults born extremely preterm compared with control participants born at term and to evaluate trajectories of health status from adolescence to early adulthood. STUDY
designThe EPICure study comprises all births <26 weeks of gestation in the United Kingdom and Ireland in 1995 and control participants born at term recruited at age 6 years. In total, 129 participants born extremely preterm and 65 control participants were followed up at the 19-year assessment. HRQL was measured by the Health Utilities Index Mark 3 multiattribute utility (MAU) scores. Only parent-reported HRQL was available at 11 years of age.
resultsParticipants born extremely preterm without neurodevelopmental impairment had significantly lower MAU scores at 19 years than controls (median [IQR]: 0.91 [0.79, 0.97] vs 0.97 [0.87, 1.00], P = .008); those with impairment had the lowest scores (0.74 [0.49, 0.90]). A 0.03-0.05 difference is considered clinically significant. Parent-reported findings were similar. Participants born extremely preterm with impairment rated their health significantly better than their parents did (0.74 vs 0.58, P = .01), in contrast to those without impairment and controls. Between 11 and 19 years, median parent-reported MAU scores decreased from 0.87 to 0.77 for participants born extremely preterm (P = .01) and from 1.00 to 0.97 for control participants (P = .02).
conclusionsAmong young adults born extremely preterm, both participants and parents rated their health status less favorably than control participants born at term. The decline in MAU scores from adolescence to early adulthood following extremely preterm birth indicates continuing health issues in young adult life.
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