Evidence map›Paper›PMID 33836104›Full record

ArticleAnnals of neurology2021

Approaches to understanding COVID-19 and its neurological associations.

Ettore Beghi, Benedict D Michael, Tom Solomon, Erica Westenberg, Andrea S Winkler, COVID-19 Neuro Research Coalition

Abstract read
In one paragraph

Article in Annals of neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Blood neurofilament light chain and S100B as biomarkers of neurological involvement and functional prognosis in COVID-19: a multicenter study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Observational
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Neurological effects of COVID-19 in infants and children.Developmental medicine and child neurology · 2022
    Review
  12. Article
  13. Article
  14. Review
  15. Review
  16. Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ettore BeghiLaboratorio di Malattie Neurologiche, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milano, Italy.
Benedict D MichaelInstitute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom.
Tom SolomonNIHR Health Protection Research Unit in Emerging and Zoonotic Infections, Liverpool, United Kingdom.
Erica WestenbergDepartment of Neurology, Center for Global Health, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.ORCID https://orcid.org/0000-0001-8297-3962
Andrea S WinklerDepartment of Neurology, Center for Global Health, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
COVID-19 Neuro Research Coalition

Funding

Medical Research Council MR/V007181/1Medical Research Council MR/V03605X/1
6 · The paper itself

Abstract

There is an accumulating volume of research into neurological manifestations of COVID-19. However, inconsistent study designs, inadequate controls, poorly-validated tests, and differing settings, interventions, and cultural norms weaken study quality, comparability, and thus the understanding of the spectrum, burden and pathophysiology of these complications. Therefore, a global COVID-19 Neuro Research Coalition, together with the WHO, has reviewed reports of COVID-19 neurological complications and harmonised clinical measures for future research. This will facilitate well-designed studies using precise, consistent case definitions of SARS-CoV2 infection and neurological complications, with standardised forms for pooled data analyses that non-specialists can use, including in low-income settings. This article is protected by copyright. All rights reserved.

Identifiers

PMID33836104
PMCPMC8250622

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.