SynthesisAesthetic surgery journal2022
Implants and Breast Pocket Irrigation: Outcomes of Antibiotic, Antiseptic, and Saline Irrigation.
Synthesis in Aesthetic surgery journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- Efficacy of antibiotic prophylaxis for reducing capsular contracture in prosthesis-based breast surgery: a systemic review and meta-analysis.Updates in surgery · 2024Pooled it
- Hypochlorous acid irrigation reduces the rate of infections in patients undergoing implant-based breast reconstruction.JPRAS open · 2026Article
- A Bibliometric Review of Capsular Contracture in Breast Implant: Global Trends and Research Hotspots.Plastic surgery (Oakville, Ont.) · 2026Article
- A randomized controlled trial: application of inactivatedGland surgery · 2026Article
- The Impact of Irrigating Solutions on the Tensile Strength of Silicone Breast Implants: A Comparative In Vitro Analysis for Intraoperative use.Plastic surgery (Oakville, Ont.) · 2026Article
- Article
- Irrigation Solutions in Wound Care and Breast Surgery: Evidence-Based Applications, Regulatory Considerations, and Future Directions.Journal of clinical medicine · 2025Article
- A Rebuttal of a Meta-analysis Supporting Breast Implant Pocket Antimicrobial Irrigation.Annals of plastic surgery · 2025Article
- Concentration of Povidone-Iodine Pocket Irrigation in Implant-Based Breast Surgery: A Scoping Review.Aesthetic plastic surgery · 2025Article
- Does the Omission of Cefazolin in Irrigation Solution Affect Outcomes in Prepectoral Direct-to-Implant Breast Reconstruction?Aesthetic plastic surgery · 2025Article
- Recurrent Allergic Contact Dermatitis to Bacitracin Used in Pocket Irrigation During Breast Reconstruction Surgery.Plastic surgery (Oakville, Ont.) · 2024Article
- Technical Refinements for Reducing Reoperations in Single-Stage Augmentation Mastopexy: A Retrospective Matched Cohort Study.Aesthetic plastic surgery · 2024Article
- Clinical Evaluation of Microbial Communities and Associated Biofilms with Breast Augmentation Failure.Microorganisms · 2024Article
- A review on antimicrobial strategies in mitigating biofilm-associated infections on medical implants.Current research in microbial sciences · 2024Review
- Article
- Advances on Capsular Contracture-Prevention and Management Strategies: A Narrative Review of the Literature.Plastic and reconstructive surgery. Global open · 2023Article
- Did the National Ban on Bacitracin Irrigation Affect Infection Rates in Implant-Based Breast Reconstruction? An Analysis of a National Database.Clinical breast cancer · 2023Article
- The Role of Microorganisms in the Development of Breast Implant-Associated Anaplastic Large Cell Lymphoma.Pathogens (Basel, Switzerland) · 2023Review
- Antiseptic Techniques in Breast Implant Surgery: Insights From Plastic Surgeons in Saudi Arabia.Aesthetic surgery journal. Open forum · 2023Article
- Keller Funnel Efficacy in "No Touch" Breast Augmentation and Reconstruction: A Systematic Review.Plastic and reconstructive surgery. Global open · 2022Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBreast implant-associated infection and capsular contracture are challenging complications that can result in poor outcomes following implant-based breast surgery. Antimicrobial irrigation of the breast pocket or implant is a widely accepted strategy to prevent these complications, but the literature lacks an evidence-based consensus on the optimal irrigation solution.
objectivesThe objective of this systematic review was to compare clinical outcomes, specifically capsular contracture, infection, and reoperation rates, associated with the use of antibiotic, antiseptic, and saline irrigation.
methodsA systematic review was performed in March 2020 based on the following search terms: "breast implant," "irrigation," "antibiotic," "bacitracin," "antiseptic," "povidone iodine," "betadine," "low concentration chlorhexidine," and "hypochlorous acid." Capsular contracture, infection, and reoperation rates were compared by analysis of forest plots.
resultsOut of the 104 articles screened, 14 met the inclusion criteria. There was no significant difference in capsular contracture rates between antibiotic and povidone-iodine irrigation, although the data comparing these 2 groups were limited and confounded by the concurrent use of steroids. Antibiotic irrigation showed a significantly lower rate of capsular contracture compared with saline irrigation and a lower rate of capsular contracture and reoperation compared with no irrigation at all. Povidone-iodine was associated with lower rates of capsular contracture and reoperation compared with saline irrigation but there were no data on infection rates specific to povidone-iodine irrigation.
conclusionsOur study supports the use of antibiotics or povidone-iodine for breast implant irrigation. Further research is required to better determine which of these 2 irrigation types is superior. LEVEL OF EVIDENCE: 4:
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.