Evidence map›Paper›PMID 33836004›Full record

Observational studyPLoS neglected tropical diseases2021

Seroprevalence of chikungunya virus infection among HIV-infected adults in French Caribbean Islands of Martinique and Guadeloupe in 2015: A cross-sectional study.

Elodie Curlier, Laurence Fagour, Cécile Herrmann-Storck, Adrien Staelen, Ingrid Vingadassalom, Sébastien Breurec, Sylvie Abel, Sandrine Pierre-François, Janick Jean-Marie, Cédric Laouénan and 3 more

Registry-linked trialOpen access · goldAbstract readObservational Study
In one paragraph

Observational study in PLoS neglected tropical diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02553369 (Seroprevalence of Chikungunya at the End of the First Chikungunya Outbreak in the French Antilles Within a Sample of Patients Treated for a HIV Infection), which is not on this map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02553369 completednot on this map

Seroprevalence of Chikungunya at the End of the First Chikungunya Outbreak in the French Antilles Within a Sample of Patients Treated for a HIV Infection

TypeobservationalSponsorUniversity Hospital Center of MartiniqueRan2015 to 2016Enrolled388ConditionsHIV Infections, Chikungunya Virus InfectionArmsBiological sample collection
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 3 countries.

Elodie CurlierDepartment of Infectious Diseases, CHU de la Guadeloupe, Pointe-à-Pitre, France.ORCID 0000-0002-6105-4841
Laurence FagourDepartment of Microbiology, CHU de la Martinique, Fort-de-France, France.
Cécile Herrmann-StorckDepartment of Microbiology, CHU de la Guadeloupe, Pointe-à-Pitre, France.
Adrien StaelenDepartment of Infectious Diseases, CHU de la Martinique, Fort-de-France, France.
Ingrid VingadassalomUniversité des Antilles, EA 4537, Fort de France, France.
Sébastien BreurecDepartment of Microbiology, CHU de la Guadeloupe, Pointe-à-Pitre, France.
Sylvie AbelDepartment of Infectious Diseases, CHU de la Martinique, Fort-de-France, France.ORCID 0000-0002-3351-0547
Sandrine Pierre-FrançoisDepartment of Infectious Diseases, CHU de la Martinique, Fort-de-France, France.
Janick Jean-MarieUniversité des Antilles, EA 4537, Fort de France, France.ORCID 0000-0001-6230-6468
Cédric LaouénanINSERM, IAME, UMR 1137; Université Paris Diderot, Paris, France.ORCID 0000-0002-3681-6314
Raymond CésaireDepartment of Microbiology, CHU de la Martinique, Fort-de-France, France.
Bruno HoenDepartment of Infectious Diseases, CHU de la Guadeloupe, Pointe-à-Pitre, France.ORCID 0000-0003-3070-3017
André CabiéINSERM Centre d'Investigation Clinique Antilles-Guyane, Cayenne, France.ORCID 0000-0003-0117-3061
Centre Hospitalier Universitaire de Martinique · MQInserm · FRCentre Hospitalier Universitaire Pointe-à-Pitre · GP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn 2014, a first outbreak of chikungunya hit the Caribbean area where chikungunya virus (CHIKV) had never circulated before. METHODOLOGY/PRINCIPAL

findingsWe conducted a cross-sectional study to measure the seroprevalence of CHIKV immediately after the end of the 2014 outbreak in HIV-infected people followed up in two clinical cohorts at the University hospitals of Guadeloupe and Martinique. Study patients were identified during the first months of 2015 and randomly selected to match the age and sex distribution of the general population in the two islands. They were invited to complete a survey that explored the symptoms consistent with chikungunya they could have developed during 2014 and to have a blood sample drawn for CHIKV serology. The study population consisted of 377 patients (198 in Martinique and 179 in Guadeloupe, 178 men and 199 women), 182 of whom reported they had developed symptoms consistent with chikungunya. CHIKV serology was positive in 230 patients, which accounted for an overall seroprevalence rate of 61% [95%CI 56-66], with only 153 patients who reported symptoms consistent with chikungunya. Most frequent symptoms included arthralgia (94.1%), fever (73.2%), myalgia (53.6%), headache (45.8%), and skin rash (26.1%). CONCLUSIONS/SIGNIFICANCE: This study showed that the seroprevalence of CHIKV infection was 61% after the 2014 outbreak, with one third of asymptomatic infections.

trial registrationClinicalTrials.gov NCT02553369.

Indexed as

Disease OutbreaksAdultArthralgiaChikungunya FeverChikungunya virusCross-Sectional StudiesExanthemaFemaleFeverGuadeloupeHeadacheHIV InfectionsHumansMaleMartiniqueMiddle Aged

Identifiers

PMID33836004
PMCPMC8059839
OpenAlexW3141134585

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.