Evidence map›Paper›PMID 33835970›Full record

ArticlePancreas2021

A National Assessment of Optimal Oncologic Surgery for Distal Pancreatic Adenocarcinomas.

Katherine Hrebinko, Samer Tohme, Richard S Hoehn, Samer AlMasri, Sidrah Khan, Christof Kaltenmeier, Kenneth K Lee, Alessandro Paniccia, Amer Zureikat, Ibrahim Nassour

Abstract read
In one paragraph

Article in Pancreas, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Preoperative weight loss and postoperative pancreatic fistula risk affected by body mass index: a National Surgical Quality Improvement Program study.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Katherine HrebinkoFrom the Division of Surgical Oncology, Department of Surgery, University of Pittsburgh Medical Center Cancer Pavilion, Pittsburgh, PA.
Samer Tohme
Richard S Hoehn
Samer AlMasri
Sidrah Khan
Christof Kaltenmeier
Kenneth K Lee
Alessandro Paniccia
Amer Zureikat
Ibrahim Nassour

Funding

Postdoctoral Research Training in Biotherapy of CancerT32CA113263 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Udai S Kammula · 2006 to 2026
$3.6M
NCI NIH HHS T32 CA113263
6 · The paper itself

Abstract

objectivesThe objective of this study was to create a composite measure, optimal oncologic surgery (OOS), for patients undergoing distal pancreatectomy for pancreatic adenocarcinoma and identify factors associated with OOS.

methodsAdult patients undergoing distal pancreatectomy were identified from the National Cancer Database between 2010 and 2016. Patients were stratified based on receipt of OOS. Criteria for OOS included 90-day survival, no 30-day readmission, length of stay ≤7 days, negative resection margins, ≥12 lymph nodes harvested, and receipt of chemotherapy. Multivariate logistic regression was performed to identify predictors of OOS. Survival curves and a Cox proportional hazards model were created to compare survival and identify risk factors for mortality.

resultsThree thousand five hundred forty-six patients were identified. The rate of OOS was 22.3%. Diagnosis after 2012, treatment at an academic medical center, and a minimally invasive surgical approach (MIS) were associated with OOS. Survival was superior for patients undergoing OOS. Decreasing age at diagnosis, fewer comorbidities, surgery at an academic medical center, MIS, and lower pathologic stage were also associated with improved survival on multivariate analysis.

conclusionsRates of OOS for distal pancreatectomy are low. Time trends show increasing rates of OOS that may be related to increasing MIS, adjuvant chemotherapy, and referrals to academic medical centers.

Indexed as

AdenocarcinomaAgedDatabases, FactualFemaleHumansKaplan-Meier EstimateLength of StayLogistic ModelsMaleMultivariate AnalysisOutcome Assessment, Health CarePancreatectomyPancreatic NeoplasmsPatient ReadmissionProportional Hazards ModelsUnited States

Identifiers

PMID33835970
PMCPMC8670387

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.