Evidence map›Paper›PMID 33835766›Full record

ArticleJournal of Zhejiang University. Science. B2021

Development and validation of an individualized nomogram for early prediction of the duration of SARS-CoV-2 shedding in COVID-19 patients with non-severe disease.

Shijin Yuan, Yong Pan, Yan Xia, Yan Zhang, Jiangnan Chen, Wei Zheng, Xiaoping Xu, Xinyou Xie, Jun Zhang

Open access · bronzeAbstract readMulticenter Study
In one paragraph

Article in Journal of Zhejiang University. Science. B, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Shijin YuanDepartment of Clinical Laboratory, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310016, China.
Yong PanDepartment of Clinical Laboratory, Wenzhou Central Hospital, Wenzhou 325099, China.
Yan XiaDepartment of Clinical Laboratory, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310016, China.
Yan ZhangDepartment of Clinical Laboratory, Xixi Hospital of Hangzhou, Hangzhou 310023, China.
Jiangnan ChenDepartment of Clinical Laboratory, Affiliated Hospital of Shaoxing University, Shaoxing 312099, China.
Wei ZhengDepartment of Clinical Laboratory, the Third People's Hospital of Yueqing, Wenzhou 325604, China.
Xiaoping XuDepartment of Clinical Laboratory, Jinhua Municipal Central Hospital, Jinhua 321099, China.
Xinyou XieDepartment of Clinical Laboratory, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310016, China. scottxie@zju.edu.cn.
Jun ZhangDepartment of Clinical Laboratory, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310016, China. jameszhang2000@zju.edu.cn.
Sir Run Run Shaw Hospital · CNHangzhou Xixi hospital · CNJinhua Central Hospital · CNShaoxing University · CNWenzhou Central Hospital · CNYueqing People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the number of cases of coronavirus disease-2019 (COVID-19) increasing rapidly, the World Health Organization (WHO) has recommended that patients with mild or moderate symptoms could be released from quarantine without nucleic acid retesting, and self-isolate in the community. This may pose a potential virus transmission risk. We aimed to develop a nomogram to predict the duration of viral shedding for individual COVID-19 patients. This retrospective multicentric study enrolled 135 patients as a training cohort and 102 patients as a validation cohort. Significant factors associated with the duration of viral shedding were identified by multivariate Cox modeling in the training cohort and combined to develop a nomogram to predict the probability of viral shedding at 9, 13, 17, and 21 d after admission. The nomogram was validated in the validation cohort and evaluated by concordance index (C-index), area under the curve (AUC), and calibration curve. A higher absolute lymphocyte count (

Indexed as

NomogramsVirus SheddingAgedAged, 80 and overAntibodies, ViralArea Under CurveCOVID-19FemaleHumansLymphocyte CountMaleMiddle AgedProportional Hazards ModelsRetrospective StudiesViral LoadAntibodies, ViralCoronavirus disease-2019 (COVID-19)Duration of viral sheddingNomogramSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

Identifiers

PMID33835766
PMCPMC8042531
OpenAlexW3148872219

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.