Evidence map›Paper›PMID 33835725›Full record

ArticlePediatric pulmonology2021

Central airway issues in bronchopulmonary dysplasia.

Erik B Hysinger

Open access · greenAbstract read
In one paragraph

Article in Pediatric pulmonology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Novel murine partial tracheal occlusion model with altered respiratory dynamics.American journal of physiology. Lung cellular and molecular physiology · 2025
    Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Use of mucolytics and inhaled antibiotics in the NICU.Journal of perinatology : official journal of the California Perinatal Association · 2025
    Review
  8. Observational
  9. Airway diseases in very low birth weight infants.Journal of perinatology : official journal of the California Perinatal Association · 2025
    Article
  10. Article
  11. Review
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Erik B HysingerCincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.ORCID 0000-0002-9222-898X
Cincinnati Children's Hospital Medical Center · US

Funding

MRI Phenotyping of Severe BPD and Prediction of OutcomesR01HL146689 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI JASON C WOODS · 2019 to 2026
$4.6M
NHLBI NIH HHS R01 HL146689
6 · The paper itself

Abstract

While there is a very large focus on the abnormalities of parenchymal lung development and extensive efforts to minimize alveolar damage with "gentle ventilation" and noninvasive respiratory support for neonates with bronchopulmonary dysplasia (BPD), there is relatively little consideration for the implications of central airway disease in this patient population. There are significant changes in the structure and conformation of the central airway during the last half of gestation, and premature birth disrupts this natural developmental process. The arrest of maturation results in a smaller airway that is more compliant, easier to deform, and more susceptible to damage. Consequently, neonates with BPD are prone to developing central airway pathology, particularly for patients who require intubation and positive pressure ventilation. Central airway disease can be divided into dynamic and fixed airway obstruction and results in increased respiratory morbidity in neonates with chronic lung disease of prematurity.

Indexed as

Airway ObstructionBronchopulmonary DysplasiaPremature BirthHumansInfant, NewbornIntermittent Positive-Pressure VentilationPositive-Pressure Respirationbronchopulmonary dysplasiabronchoscopyneonatal pulmonary medicine

Identifiers

PMID33835725
PMCPMC8656371
OpenAlexW3142111699

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.