Evidence map›Paper›PMID 33835399›Full record

ArticleJournal of molecular neuroscience : MN2021

CircUBQLN1 Promotes Proliferation but Inhibits Apoptosis and Oxidative Stress of Hippocampal Neurons in Epilepsy via the miR-155-Mediated SOX7 Upregulation.

Zhujun Zhu, Sihong Wang, Qi Cao, Gang Li

Abstract read
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In one paragraph

Article in Journal of molecular neuroscience : MN, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Zhujun ZhuDepartment of Neurology, The First People's Hospital of Jintan District, Changzhou City, 213200, Jiangsu Province, China.
Sihong WangDepartment of Neurology, The First People's Hospital of Jintan District, Changzhou City, 213200, Jiangsu Province, China.
Qi CaoDepartment of Neurology, Changzhou Third People's Hospital, Changzhou, 213000, Jiangsu, China.
Gang LiDepartment of Neurology, Changzhou Third People's Hospital, Changzhou, 213000, Jiangsu, China. ligang_toddy@163.com.ORCID http://orcid.org/0000-0001-7785-1549
Changzhou Third People's Hospital · CNJiangsu University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Circular RNAs (circRNAs) have key roles in a variety of neurological diseases, including epilepsy. This objective of this study was to perform the functional exploration and mechanism investigation of circRNA Ubiquilin1 (circUBQLN1) in epilepsy. Epilepsy cell model was established by the treatment of Mg

Indexed as

ApoptosisAdaptor Proteins, Signal TransducingAutophagy-Related ProteinsCell LineCell ProliferationEpilepsy, Temporal LobeHippocampusHumansMicroRNAsNeuronsOxidative StressRNA, CircularSOXF Transcription FactorsUp-RegulationAdaptor Proteins, Signal TransducingAutophagy-Related ProteinsMicroRNAsMIRN155 microRNA, humanRNA, CircularSOX7 protein, humanSOXF Transcription FactorsUBQLN1 protein, humanCircUBQLN1EpilepsyMiR-155SOX7

Identifiers

PMID33835399
OpenAlexW3141635498

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.