Evidence map›Paper›PMID 33835273›Full record

ArticleThe ultrasound journal2021

One-month outcomes of patients with SARS-CoV-2 infection and their relationships with lung ultrasound signs.

Thiago Thomaz Mafort, Rogério Rufino, Claudia Henrique da Costa, Mariana Soares da Cal, Laura Braga Monnerat, Patrícia Frascari Litrento, Laura Lizeth Zuluaga Parra, Arthur de Sá Earp de Souza Marinho, Agnaldo José Lopes

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in The ultrasound journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05967039 (Evaluation of Lung Function, Lung Ultrasound and Functional Capacity in Long-COVID Patients Who Underwent Physical Therapy), which is not on this map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05967039 unknown statusnot on this mapstarted 2022, after this paper: background citation

Evaluation of Lung Function, Lung Ultrasound and Functional Capacity in Long-COVID Patients Who Underwent Physical Therapy

TypeobservationalSponsorCentro Universitário Augusto MottaRan2022 to 2023Enrolled65ConditionsPost-COVID-19 Syndrome, Long COVIDArmsPhysiotherapy
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Association of Lung Ultrasound Score with Mortality and Severity of COVID-19: A Meta-Analysis and Trial Sequential Analysis.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2021
    Pooled it
  2. Review
  3. Article
  4. Review
  5. Review
  6. Observational
  7. Review
  8. Simplified Lung Ultrasound Examination and Telehealth Feasibility in Early SARS-CoV-2 Infection.Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography · 2022
    Article
  9. Outcomes of Simplified Lung Ultrasound Exam in COVID-19: Implications for Self-Imaging.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2022
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Thiago Thomaz MafortDepartment of Pulmonology, Piquet Carneiro Policlinic, State University of Rio de Janeiro, Av. Mal. Rondon, 381, São Francisco Xavier, Rio de Janeiro, 20950-003, Brazil.ORCID http://orcid.org/0000-0002-6193-4822
Rogério RufinoDepartment of Pulmonology, Piquet Carneiro Policlinic, State University of Rio de Janeiro, Av. Mal. Rondon, 381, São Francisco Xavier, Rio de Janeiro, 20950-003, Brazil.ORCID http://orcid.org/0000-0002-5071-6045
Claudia Henrique da CostaDepartment of Pulmonology, Piquet Carneiro Policlinic, State University of Rio de Janeiro, Av. Mal. Rondon, 381, São Francisco Xavier, Rio de Janeiro, 20950-003, Brazil.ORCID http://orcid.org/0000-0001-6785-0753
Mariana Soares da CalDepartment of Pulmonology, Piquet Carneiro Policlinic, State University of Rio de Janeiro, Av. Mal. Rondon, 381, São Francisco Xavier, Rio de Janeiro, 20950-003, Brazil.ORCID http://orcid.org/0000-0001-5537-7057
Laura Braga MonneratDepartment of Pulmonology, Piquet Carneiro Policlinic, State University of Rio de Janeiro, Av. Mal. Rondon, 381, São Francisco Xavier, Rio de Janeiro, 20950-003, Brazil.ORCID http://orcid.org/0000-0003-3798-400X
Patrícia Frascari LitrentoDepartment of Pulmonology, Piquet Carneiro Policlinic, State University of Rio de Janeiro, Av. Mal. Rondon, 381, São Francisco Xavier, Rio de Janeiro, 20950-003, Brazil.ORCID http://orcid.org/0000-0001-7405-4480
Laura Lizeth Zuluaga ParraDepartment of Pulmonology, Piquet Carneiro Policlinic, State University of Rio de Janeiro, Av. Mal. Rondon, 381, São Francisco Xavier, Rio de Janeiro, 20950-003, Brazil.ORCID http://orcid.org/0000-0002-6375-4286
Arthur de Sá Earp de Souza MarinhoDepartment of Pulmonology, Piquet Carneiro Policlinic, State University of Rio de Janeiro, Av. Mal. Rondon, 381, São Francisco Xavier, Rio de Janeiro, 20950-003, Brazil.ORCID http://orcid.org/0000-0002-0877-8613
Agnaldo José LopesDepartment of Pulmonology, Piquet Carneiro Policlinic, State University of Rio de Janeiro, Av. Mal. Rondon, 381, São Francisco Xavier, Rio de Janeiro, 20950-003, Brazil. agnaldolopes.uerj@gmail.com.ORCID http://orcid.org/0000-0001-8598-4878
Universidade do Estado do Rio de Janeiro · BRUniversity Center Augusto Motta · BR

Funding

Lacrimal Gland Repair Using Progenitor CellsR01EY026202 · NEI · SCRIPPS RESEARCH INSTITUTE, THE · PI MAKARENKOVA, HELEN P. · 2016 to 2025
$5.2M
Conselho Nacional de Desenvolvimento Científico e Tecnológico 302215/2019-0Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro #E-26/202.679/2018 and #E-26/010.002124/2019
6 · The paper itself

Abstract

backgroundThe role of lung ultrasound (LUS) in evaluating the mid- and long-term prognoses of patients with COVID-19 pneumonia is not yet known. The objectives of this study were to evaluate associations between LUS signs at the time of screening and clinical outcomes 1 month after LUS and to assess LUS signs at the time of presentation with known risk factors for COVID-19 pneumonia.

methodsThis was a retrospective study of data prospectively collected 1 month after LUS screening of 447 adult patients diagnosed with COVID-19 pneumonia. Sonographic examination was performed in screening tents with the participants seated. The LUS signs (B-lines > 2, coalescent B-lines, and subpleural consolidations) were captured in six areas of each hemithorax and a LUS aeration score was calculated; in addition, the categories of disease probability based on patterns of LUS findings (high-probability, intermediate-probability, alternate, and low-probability patterns) were evaluated. The LUS signs at patients' initial evaluation were related to the following outcomes: symptomatology, the need for hospitalization or invasive mechanical ventilation (IMV), and COVID-19-related death.

resultsAccording to the evaluations performed 1 month after LUS screening, 36 patients were hospitalised, eight of whom required intensive care unit (ICU) admission and three of whom died. The presence of coalescent B-lines was associated with the need for hospitalization (p = 0.008). The presence of subpleural consolidations was associated with dyspnoea (p < 0.0001), cough (p = 0.003), the need for hospitalization (p < 0.0001), the need for ICU admission (p < 0.0001), and death (p = 0.002). A higher aeration score was associated with dyspnoea (p < 0.0001), the need for hospitalization (p < 0.0001), the need for ICU admission (p < 0.0001), and death (p = 0.003). In addition, patients with a high-probability LUS pattern had a higher aeration score (p < 0.0001) and more dyspnoea (p = 0.024) and more often required hospitalization (p < 0.0001) and ICU admission (p = 0.031).

conclusionsIn patients with COVID-19 pneumonia, LUS signs were related to respiratory symptoms 1 month after LUS screening. Strong relationships were identified between LUS signs and the need for hospitalization and death.

Indexed as

1-month outcomesCOVID-19Lung ultrasoundPneumoniaSARS-CoV-2

Identifiers

PMID33835273
PMCPMC8033556
OpenAlexW3151087886

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.