Evidence map›Paper›PMID 33835219›Full record

ArticleWorld journal of surgery2021

Spare Parathyroid Glands During Thyroid Surgery with Perioperative Autofluorescence Imaging: A Diagnostic Study.

Alexandre Bellier, Yann Wazne, Thibaut Chollier, Nathalie Sturm, Philippe Chaffanjon

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Article in World journal of surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Alexandre BellierClinical Research Department, CIC 1406, INSERM, Grenoble Alpes University, CS 10217, 38043, Grenoble Cedex 09, France. abellier@chu-grenoble.fr.ORCID http://orcid.org/0000-0003-0907-0315
Yann WazneDepartment of Endocrine Surgery, Grenoble Alpes University Hospital, Grenoble Cedex 09, France.
Thibaut ChollierDepartment of Endocrine Surgery, Grenoble Alpes University Hospital, Grenoble Cedex 09, France.
Nathalie SturmDepartment of Pathology, Grenoble Alpes University Hospital, Grenoble Cedex 09, France.
Philippe ChaffanjonDepartment of Endocrine Surgery, Grenoble Alpes University Hospital, Grenoble Cedex 09, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this original study was to determine the number of parathyroid glands that can be saved and reimplanted thanks to autofluorescence during thyroid surgery. Preservation of parathyroid function remains challenging during thyroid surgery. The parathyroid glands must be identified and immediately autotransplanted in the case of devascularization. Near-infrared autofluorescence of parathyroid glands has recently been proposed to help surgeons during the dissection.

methodsA total of 116 thyroid lobectomies were performed on 70 consecutive adult patients. Each lobectomy specimen was scanned in vitro with an autofluorescence imaging device. Every spot of autofluorescence was examined by the surgeon and subsequently the pathologist. The pathologist also performed a complete study of the rest of the lobe. We compared the results of the macroscopic and microscopic diagnoses.

resultsWe detected 24 fluorescent spots on the specimens: 13 were considered to be parathyroid tissue by the surgeon and 11, non-parathyroid tissue. The pathologist confirmed the surgical diagnosis but also discovered 15 additional parathyroid glands that were hidden.

conclusionsAutofluorescence imaging of the thyroidectomy specimen with surgical inspection is safe, quick, noninvasive and can help detect the accidental removal of parathyroid glands. About 60% of these glands can be spared and autotransplanted during the surgery.

Indexed as

Parathyroid GlandsThyroid GlandAdultDiagnostic Tests, RoutineHumansOptical ImagingThyroidectomy

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.