ArticlePediatric radiology2021
Pediatric solid intra-articular masses of the knee: prevalence, imaging features and etiologies.
Article in Pediatric radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 5 citations in OpenAlex.
- Soft tissue and juxtaarticular tumors of the knee.Skeletal radiology · 2026Review
- MRI features of joint capsule-originating hamartomas in a pediatric patient with tuberous sclerosis: a novel case report.Skeletal radiology · 2026Article
- Tenosynovial giant cell tumor and its differential diagnosis in children.Pediatric radiology · 2025Review
- Delayed diagnosis of pediatric intra-articular epithelioid sarcoma: a case report and literature review.BMC pediatrics · 2023Review
- Primary synovial sarcoma of the shoulder: Case report of the "triple sign" on proton density magnetic resonance imaging.Radiology case reports · 2023Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe etiologies of pediatric solid intra-articular soft-tissue masses are not well described and can present diagnostic dilemmas.
objectiveOur hypothesis was that these entities have a limited differential diagnosis and are mostly benign. MATERIALS AND
methodsWe reviewed knee magnetic resonance imaging (MRI) scans performed at our tertiary care institution between 2001 and 2019 (n=3,915). Our inclusion criterion was knee MRI with a solid intra-articular soft-tissue mass. Our exclusion criteria were cases with no masses or non-solid intra-articular lesions with clear radiologic diagnoses. Multiple radiologic characteristics were evaluated. Radiologic and histological diagnoses were collected when available. Cases without histology were assigned a suspected diagnosis.
resultsTwenty-five out of 3,915 (<1%) cases met the inclusion/exclusion criteria. Twenty patients underwent biopsy. Patient age ranged from 1 to 19 years with a mean age of 12 years. Lesion size ranged from 1 to 7 cm with a mean of 3.3 cm. The top three histological diagnoses were pigmented villonodular synovitis (PVNS) (7/20, 35%), vascular malformations (2/20, 10%) and inflammatory arthritis (2/20, 10%). There was one malignant case of synovial sarcoma (1/20, 5%). Of the five cases without biopsies, PVNS was the most common diagnosis (3/5, 60%). Five out of 10 (50%) PVNS cases were focal and 5/10 (50%) were multifocal. All PVNS cases (10/10, 100%) had hypointense signal on T2.
conclusionSolid intra-articular soft-tissue masses of the knee in children are rare, with a prevalence of <1% in our study. The vast majority are benign with PVNS being the most common diagnosis.
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