ArticleSocial cognitive and affective neuroscience2021
Gray matter correlates of impulsivity in psychopathy and in the general population differ by kind, not by degree: a comparison of systematic reviews.
Article in Social cognitive and affective neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- Brain gray matter structures associated with trait impulsivity: A systematic review and voxel-based meta-analysis.Human brain mapping · 2021Pooled it
- Cortical Structure in Relation to Empathy and Psychopathy in 800 Incarcerated Men.Biological psychiatry global open science · 2026Article
- Cortical structure in relation to empathy and psychopathy in 800 incarcerated men.bioRxiv : the preprint server for biology · 2025Article
- Neurobehavioral features in medication-overuse headache.eNeurologicalSci · 2024Article
- Dietary Intakes of Long-Chain Polyunsaturated Fatty Acids and Impulsivity: Comparing Non-Restricted, Vegetarian, and Vegan Diets.Nutrients · 2024Observational
- Disgust sensitivity and psychopathic behavior: A narrative review.Translational neuroscience · 2024Review
- A neurocognitive model of early onset persistent and desistant antisocial behavior in early adulthood.Frontiers in human neuroscience · 2023Review
- Value-based decision-making network functional connectivity correlates with substance use and delay discounting behaviour among young adults.NeuroImage. Clinical · 2023Article
- A multidimensional examination of psychopathy traits and gray matter volume in adults.Social cognitive and affective neuroscience · 2022Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
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Abstract
A fundamental question in neuropsychiatry is whether a neurobiological continuum accompanies the behavioral continuum between subclinical and clinical traits. Impulsivity is a trait that varies in the general population and manifests severely in disorders like psychopathy. Is the neural profile of severe impulsivity in psychopathy an extreme but continuous manifestation of that associated with impulsivity in the general population (different by degree)? Or is it discontinuous and unique (different by kind)? Here, we compare systematic reviews of the relationship between impulsivity and gray matter in psychopathy and in the general population. The findings suggest that the neural profile associated with extreme impulsivity in psychopathy (increased gray matter in rostral and ventral striatum and prefrontal cortexes) is distinct from that associated with impulsivity in the general population (decreased gray matter in rostral and ventral prefrontal cortexes). Severe impulsivity in psychopathy may therefore arise from a pathophysiological mechanism that is unique to the disorder. These findings prompt the need for future studies to directly test the effect of group on the impulsivity-gray matter relationship in samples comprised of healthy individuals and individuals with psychopathy. The results caution against the use of community samples to examine impulsive psychopathic traits in relation to neurobiology.
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