Evidence map›Paper›PMID 33835023›Full record

ArticleeLife2021

NusG is an intrinsic transcription termination factor that stimulates motility and coordinates gene expression with NusA.

Zachary F Mandell, Reid T Oshiro, Alexander V Yakhnin, Rishi Vishwakarma, Mikhail Kashlev, Daniel B Kearns, Paul Babitzke

Open access · goldAbstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 63 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Quantification of EctopicInternational journal of molecular sciences · 2026
    Article
  6. RNAP-seq:bioRxiv : the preprint server for biology · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Analysis of 3'-seq data from multiplebioRxiv : the preprint server for biology · 2025
    Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. How do bacteria tune transcription termination efficiency?Current opinion in microbiology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Zachary F MandellDepartment of Biochemistry and Molecular Biology, Center for RNA Molecular Biology, Pennsylvania State University, University Park, United States.
Reid T OshiroDepartment of Biology, Indiana University, Bloomington, United States.
Alexander V YakhninNCI RNA Biology Laboratory, Center for Cancer Research, NCI, Frederick, United States.ORCID 0000-0002-7313-7054
Rishi VishwakarmaDepartment of Biochemistry and Molecular Biology, Center for RNA Molecular Biology, Pennsylvania State University, University Park, United States.
Mikhail KashlevNCI RNA Biology Laboratory, Center for Cancer Research, NCI, Frederick, United States.
Daniel B KearnsDepartment of Biology, Indiana University, Bloomington, United States.
Paul BabitzkeDepartment of Biochemistry and Molecular Biology, Center for RNA Molecular Biology, Pennsylvania State University, University Park, United States.ORCID 0000-0003-2481-1062
Pennsylvania State University · USCenter for Cancer Research · USIndiana University Bloomington · US

Funding

Mechanisms of transcription pausing and fidelity in prokaryotes and eukaryotesZIABC010795 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI KASHLEV, MIKHAIL · 2009 to 2025
$18.1M
Swarming motility and the regulation of flagellar biosynthesis in Bacillus subtilisR35GM131783 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI Daniel B Kearns · 2019 to 2026
$3.9M
Regulation of transcription elongationR01GM098399 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI BABITZKE, PAUL L · 2012 to 2024
$3.6M
NIGMS NIH HHS R01 GM098399NIGMS NIH HHS R35 GM131783NIH HHS GM098399NIH HHS GM131783
6 · The paper itself

Abstract

NusA and NusG are transcription factors that stimulate RNA polymerase pausing in

Indexed as

Gene ExpressionTranscription Termination, GeneticBacillus subtilisBacterial ProteinsBase SequenceTranscriptional Elongation FactorsBacterial ProteinsTranscriptional Elongation FactorsbiochemistryB. subtilischemical biologygene regulationinfectious diseasemicrobiologymotilityNusANusGTerm-seqtranscription termination

Identifiers

PMID33835023
PMCPMC8060035
OpenAlexW3146070150

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.