Evidence map›Paper›PMID 33834303›Full record

ArticleArchives of osteoporosis2021

Disease progression associated with low bone mass in axial spondyloarthropathy patients.

De Hao Liu, Juan Chen, Xiong Jie Zhuang, Li Chun Chen

Abstract read
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In one paragraph

Article in Archives of osteoporosis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

De Hao LiuDepartment of Radiology, The First Affiliated Hospital of Xiamen University, 55 Zhenhai Road, Siming, Xiamen, 361003, Fujian, China.
Juan ChenDepartment of Rheumatology and Immunology, The First Affiliated Hospital of Xiamen University, 55 Zhenhai Road, Siming, Xiamen, 361003, Fujian, China.
Xiong Jie ZhuangDepartment of Radiology, The First Affiliated Hospital of Xiamen University, 55 Zhenhai Road, Siming, Xiamen, 361003, Fujian, China.
Li Chun ChenDepartment of Radiology, Xiamen Hospital of Traditional Chinese Medicine, 1739 Xianyue Road, Huli, Xiamen, 361001, Fujian, China. chenlichun12141990@163.com.
First Affiliated Hospital of Xiamen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Through statistical analysis, we have found that inflammation and low femoral and lumbar spine BMD were strongly correlated with a high SIJ CT grade, and inflammation, low vitamin D levels, and a longer disease course within a certain time range influenced bone loss in axSpA. PURPOSE: We investigated the relationship between bone mineral density (BMD), vitamin D, and computed tomography (CT)-based progression of disease grades of the sacroiliac joint (SIJ), and sought to identify parameters predicting low BMD in patients with axial spondyloarthropathy (axSpA).

methodsWe collected the ankylosis spondylitis disease activity score (ASDAS), the course of the disease, HLA-B27 status, and vitamin D and C-reactive protein (CRP) levels of 98 axSpA patients. Lumbar spine and femoral BMD were assessed by dual-energy X-ray (DXA), and SIJ grade was determined by CT.

resultsThe axSpA patients (71 men, 27 women) with a mean age of 31.9 years (range 18-57 years) and body mass index 21.8 kg/m

conclusionsThus, inflammation and low femoral and lumbar spine BMD were strongly correlated with a high SIJ CT grade, and inflammation, low vitamin D levels, and a longer disease course within a certain time range influenced bone loss in axSpA.

Indexed as

SpondylarthritisSpondylarthropathiesAbsorptiometry, PhotonAdolescentAdultAgedBone DensityDisease ProgressionFemaleHumansLumbar VertebraeMaleMiddle AgedYoung AdultBone mineral densityComputed tomography gradeSpondyloarthropathyVitamin D

Identifiers

PMID33834303
OpenAlexW3144554405

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.