Evidence map›Paper›PMID 33834122›Full record

ArticleJournal of spine surgery (Hong Kong)2021

Osteoporosis is under recognized and undertreated in adult spinal deformity patients.

Anmol Gupta, Thomas Cha, Joseph Schwab, Harold Fogel, Daniel G Tobert, Afshin E Razi, Carl Paulino, Andrew C Hecht, Christopher M Bono, Stuart Hershman

Abstract read
In one paragraph

Article in Journal of spine surgery (Hong Kong), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Perioperative teriparatide for preventing proximal junctional kyphosis and failure in patients with osteoporosis after adult thoracolumbar spinal deformity surgery: a prospective randomized controlled trial.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
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  6. Personalized Approaches to Spine Surgery.International journal of spine surgery · 2024
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  8. Predictive role of FRAX© for postoperative proximal junctional kyphosis with vertebral fracture after adult spinal deformity surgery.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Anmol GuptaDepartment of Orthopaedics, The Mount Sinai Hospital, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Thomas ChaDepartment of Orthopaedics, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Joseph SchwabDepartment of Orthopaedics, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Harold FogelDepartment of Orthopaedics, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Daniel G TobertDepartment of Orthopaedics, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Afshin E RaziDepartment of Orthopaedics, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Carl PaulinoDepartment of Orthopaedic Surgery, Fe Health Sciences University, New York-Presbyterian (NYP) Brooklyn Methodist Hospital, Brooklyn, NY, USA.
Andrew C HechtDepartment of Orthopaedics, The Mount Sinai Hospital, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Christopher M BonoDepartment of Orthopaedics, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Stuart HershmanDepartment of Orthopaedics, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAdult spinal deformity (ASD) patients may have osteoporosis, predisposing them to an increased risk for surgical complications. Prior studies have demonstrated that treating osteoporosis improves surgical outcomes. In this study we determine the prevalence of osteoporosis in ASD patients undergoing long spinal fusions and the rate at which osteoporosis is treated.

methodsASD patients who frequented either of two major academic medical centers from 2010 through 2019 were studied. All study participants were at least 40 years of age and endured a spinal fusion of at least seven vertebral levels. Medical records were explored for a diagnosis of osteoporosis via ICD-10 code and, if present, whether pharmacological treatment was prescribed. T-tests and chi-squared analyses were used to determine statistical significance.

resultsThree hundred ninety-nine patients matched the study's inclusion criteria. Among this group, 131 patients (32.8%) had been diagnosed with osteoporosis prior to surgery. With a mean age of 66.4 years, osteoporotic patients were on average three years older than non-osteoporotic (P=0.002) and more likely to be female (74.8%

conclusionsThe prevalence of osteoporosis in ASD patients undergoing a long spinal fusion is substantially higher than that of the general population. Surgeons should have a low threshold for bone density testing in ASD patients. With only about one-third of osteoporotic patients treated, there is a classic "missed opportunity" in this population.

Indexed as

Deformityfusionsosteoporosisscoliosissurgical complications

Identifiers

PMID33834122
PMCPMC8024750

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.