Evidence map›Paper›PMID 33834006›Full record

ArticleFrontiers in cellular and infection microbiology2021

Neutralizing Antibodies to Severe Fever With Thrombocytopenia Syndrome Virus Among Survivors, Non-Survivors and Healthy Residents in South Korea.

Jeong Rae Yoo, Jae-Yong Kim, Sang Taek Heo, Jihye Kim, Hyeong-Jun Park, Joo-Yeon Lee, Hee-Young Lim, Woo-Jung Park, Nam-Hyuk Cho, Jung Mogg Kim and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

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  10. Development of monoclonal antibody based IgG and IgM ELISA for diagnosis of severe fever with thrombocytopenia syndrome virus infection.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 1 country.

Jeong Rae YooDepartment of Infectious Diseases, Jeju National University College of Medicine, Jeju, South Korea.
Jae-Yong KimDepartment of Medical and Biological Sciences, The Catholic University of Korea, Bucheon, South Korea.
Sang Taek HeoDepartment of Infectious Diseases, Jeju National University College of Medicine, Jeju, South Korea.
Jihye KimDepartment of Medical Nutrition, Graduate School of East-West Medical Science, Kyung Hee University, Yongin, South Korea.
Hyeong-Jun ParkDepartment of Medical and Biological Sciences, The Catholic University of Korea, Bucheon, South Korea.
Joo-Yeon LeeDivision of Emerging Infectious Diseases and Vector Research, National Institute of Health, Korea Center for Disease Control and Prevention, Osong, South Korea.
Hee-Young LimDivision of Emerging Infectious Diseases and Vector Research, National Institute of Health, Korea Center for Disease Control and Prevention, Osong, South Korea.
Woo-Jung ParkDivision of Emerging Infectious Diseases and Vector Research, National Institute of Health, Korea Center for Disease Control and Prevention, Osong, South Korea.
Nam-Hyuk ChoDepartment of Microbiology, Seoul National University College of Medicine, Seoul, South Korea.
Jung Mogg KimDepartment of Microbiology, Hanyang University College of Medicine, Seoul, South Korea.
Jae-Hwan NamDepartment of Medical and Biological Sciences, The Catholic University of Korea, Bucheon, South Korea.
Keun Hwa LeeDepartment of Microbiology, Hanyang University College of Medicine, Seoul, South Korea.
Kyung Hee University · KRKorea Center for Disease Control and Prevention · KRSeoul National University · KRThe Catholic University of Korea Bucheon St. Mary's Hospital · KRHanyang University · KRJeju National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe fever with thrombocytopenia syndrome (SFTS), a newly emerging tick-borne viral disease, has been detected in Asia since 2009, and person-to-person transmission is possible. SFTS is characterized by atypical signs, including mild to severe febrile illness similar to that associated with hemorrhagic fever, with 16.2 to 30% mortality. We found that the titers of neutralizing antibodies, play an important role in protective immunity, to SFTS virus (SFTSV) in survivors and healthy residents who lived in endemic areas and who were positive for SFTSV IgG, were higher than those in non-survivor patients. Moreover, the titers were maintained in surviving patients and healthy residents but not in non-surviving patients in South Korea.

Indexed as

Bunyaviridae InfectionsPhlebovirusSevere Fever with Thrombocytopenia SyndromeAntibodies, NeutralizingAsiaHumansRepublic of KoreaSurvivorsAntibodies, Neutralizinghealthy residentsneutralizing antibodiesnon-survivorsSFTSVSouth Koreasurvivors

Identifiers

PMID33834006
PMCPMC8021957
OpenAlexW3137349256

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.