Evidence map›Paper›PMID 33834005›Full record

ArticleFrontiers in cellular and infection microbiology2021

Trypanosome KKIP1 Dynamically Links the Inner Kinetochore to a Kinetoplastid Outer Kinetochore Complex.

Lorenzo Brusini, Simon D'Archivio, Jennifer McDonald, Bill Wickstead

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 24 citations in OpenAlex.

  1. Biomolecular NMR assignments · 2025
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Lessons from the deep: mechanisms behind diversification of eukaryotic protein complexes.Biological reviews of the Cambridge Philosophical Society · 2023
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Kinetochore Architecture Employs Diverse Linker Strategies Across Evolution.Frontiers in cell and developmental biology · 2022
    Review
  14. Review
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Lorenzo BrusiniSchool of Life Sciences, University of Nottingham, Nottingham, United Kingdom.
Simon D'ArchivioSchool of Life Sciences, University of Nottingham, Nottingham, United Kingdom.
Jennifer McDonaldSchool of Life Sciences, University of Nottingham, Nottingham, United Kingdom.
Bill WicksteadSchool of Life Sciences, University of Nottingham, Nottingham, United Kingdom.
University of Nottingham · GBUniversity of Geneva · CH

Funding

Biotechnology and Biological Sciences Research Council 1364116Biotechnology and Biological Sciences Research Council BB/J01477X/1Medical Research Council 1506963Wellcome Trust 204843/Z/16/Z
6 · The paper itself

Abstract

Kinetochores perform an essential role in eukaryotes, coupling chromosomes to the mitotic spindle. In model organisms they are composed of a centromere-proximal inner kinetochore and an outer kinetochore network that binds to microtubules. In spite of universal function, the composition of kinetochores in extant eukaryotes differs greatly. In trypanosomes and other Kinetoplastida, kinetochores are extremely divergent, with most components showing no detectable similarity to proteins in other systems. They may also be very different functionally, potentially binding to the spindle directly

Indexed as

KinetochoresTrypanosomaMicrotubulesSpindle Apparatuscell divisionchromosome segregationevolutionary biologykinetochoreTrypanosoma

Identifiers

PMID33834005
PMCPMC8023272
OpenAlexW3136654468

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.