Evidence map›Paper›PMID 33833996›Full record

ArticleFrontiers in oncology2021

Circulating miR-320a Acts as a Tumor Suppressor and Prognostic Factor in Non-small Cell Lung Cancer.

Akanksha Khandelwal, Uttam Sharma, Tushar Singh Barwal, Rajeev Kumar Seam, Manish Gupta, Manjit Kaur Rana, Karen M Vasquez, Aklank Jain

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
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  8. [Predictive Value of A miRNA Signature for Distant Metastasis in Lung Cancer].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2024
    Article
  9. Review
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  17. The Effect of MiR320a on Lung Cancer.MicroRNA (Shariqah, United Arab Emirates) · 2024
    Review
  18. Review
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Akanksha KhandelwalDepartment of Biochemistry and Microbial Sciences, Central University of Punjab, Bathinda, India.
Uttam SharmaDepartment of Zoology, Central University of Punjab, Bathinda, India.
Tushar Singh BarwalDepartment of Zoology, Central University of Punjab, Bathinda, India.
Rajeev Kumar SeamDepartment of Radiation Oncology, Indira Gandhi Medical College, Shimla, India.
Manish GuptaDepartment of Radiation Oncology, Indira Gandhi Medical College, Shimla, India.
Manjit Kaur RanaLab Medicine, Department of Pathology, All India Institute of Medical Sciences, Bathinda, India.
Karen M VasquezDivision of Pharmacology and Toxicology, College of Pharmacy, Dell Pediatric Research Institute, The University of Texas at Austin, Austin, TX, United States.
Aklank JainDepartment of Zoology, Central University of Punjab, Bathinda, India.
Central University of Punjab · INIndira Gandhi Medical College · INAll India Institute of Medical Sciences · INThe University of Texas at Austin · US

Funding

REPAIR OF GENOME DESTABILIZING DNA STRUCTURESR01CA093729 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Karen M Vasquez · 2002 to 2026
$8.2M
NCI NIH HHS R01 CA093729
6 · The paper itself

Abstract

Dysregulated expression profiles of microRNAs (miRNAs) have been observed in several types of cancer, including non-small cell lung cancer (NSCLC); however, the diagnostic and prognostic potential of circulating miRNAs in NSCLC remains largely undefined. Here we found that circulating miR-320a was significantly down-regulated (~5.87-fold;

Indexed as

cancerliquid biopsymiR-320aNSCLCprognosis

Identifiers

PMID33833996
PMCPMC8021852
OpenAlexW3137810423

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.