Evidence map›Paper›PMID 33833859›Full record

ArticleJournal of healthcare engineering2021

Association between Single Nucleotide Polymorphism rs9891119 of STAT3 Gene and the Genetic Susceptibility to Type 2 Diabetes in Chinese Han Population from Guangdong.

Haibing Yu, Xuyun Xu, Jialu Huang, Jian Xu, Hao Liu, Yuxun Xie, Chunwen Lin, Congcong Pan, Danli Kong, Yuanlin Ding

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PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of healthcare engineering, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Haibing Yu *Department of Epidemiology and Health Statistics, School of Public Health, Guangdong Medical University, Dongguan, Guangdong Province 523808, China.ORCID 0000-0002-1877-3074
Xuyun Xu *Shantou Hospital of Traditional Chinese Medicine, Shantou, Guangdong Province 515031, China.
Jialu HuangDepartment of Epidemiology and Health Statistics, School of Public Health, Guangdong Medical University, Dongguan, Guangdong Province 523808, China.
Jian XuDepartment of Epidemiology and Health Statistics, School of Public Health, Guangdong Medical University, Dongguan, Guangdong Province 523808, China.
Hao LiuDepartment of Epidemiology and Health Statistics, School of Public Health, Guangdong Medical University, Dongguan, Guangdong Province 523808, China.
Yuxun XieDepartment of Epidemiology and Health Statistics, School of Public Health, Guangdong Medical University, Dongguan, Guangdong Province 523808, China.
Chunwen LinDepartment of Epidemiology and Health Statistics, School of Public Health, Guangdong Medical University, Dongguan, Guangdong Province 523808, China.ORCID 0000-0003-1227-5370
Congcong PanDepartment of Epidemiology and Health Statistics, School of Public Health, Guangdong Medical University, Dongguan, Guangdong Province 523808, China.
Danli KongDepartment of Epidemiology and Health Statistics, School of Public Health, Guangdong Medical University, Dongguan, Guangdong Province 523808, China.ORCID 0000-0002-1661-1848
Yuanlin DingDepartment of Epidemiology and Health Statistics, School of Public Health, Guangdong Medical University, Dongguan, Guangdong Province 523808, China.ORCID 0000-0003-4057-6488
Guangdong Medical College · CNShantou Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The aim of this study was to investigate the association between single nucleotide polymorphism (SNP) rs9891119 of the signal transducer and activator of the transcription 3 (STAT3) gene and genetic susceptibility to type 2 diabetes in Chinese Han population from the Guangdong province. Objective: The aim of the present study was to explore the relationship between single nucleotide polymorphism rs9891119 of STAT3 gene and type 2 diabetes mellitus (T2DM), which provides a basis for molecular genetic research on the pathogenesis of T2DM in Chinese Han population. Methods: In our case-control study, the SNP rs9891119 was picked out from the STAT3 gene and the SNP genotyping was performed by using the SNPscan Results: Our results showed that the alleles of A and C of rs9891119 of the STAT3 gene were 54.3 and 45.7% in patients with type 2 diabetes, while 55.5% and 44.5% in the normal persons, which have no statistical significance ( Conclusions: Therefore, genetic susceptibility to type 2 diabetes may be not associated with SNP rs9891119 of the STAT3 gene in Chinese Han population from the Guangdong province.

Indexed as

Diabetes Mellitus, Type 2Genetic Predisposition to DiseaseCase-Control StudiesChinaHumansPolymorphism, Single NucleotideSTAT3 Transcription FactorTransducersSTAT3 protein, humanSTAT3 Transcription Factor

Identifiers

PMID33833859
PMCPMC8012137
OpenAlexW3137365491

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.