ArticleFrontiers in immunology2021
Integrative Clinical, Molecular, and Computational Analysis Identify Novel Biomarkers and Differential Profiles of Anti-TNF Response in Rheumatoid Arthritis.
Open access · goldAbstract readMulticenter Study
In one paragraph
Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
3.7field-weighted citation impact, top 6% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- Machine learning for predicting treatment response to biologic and targeted synthetic disease-modifying antirheumatic drugs in rheumatoid arthritis: a scoping review.BMC rheumatology · 2025Pooled it
- miRNA-Mediated Epigenetic Regulation of Treatment Response in RA Patients-A Systematic Review.International journal of molecular sciences · 2022Pooled it
- Clustering of rheumatoid arthritis patients: an unsupervised machine learning approach for characterizing the TNFi response.Immunologic research · 2026Article
- Neutrophil extracellular traps in rheumatoid arthritis: biomarkers, drivers, and emerging therapeutic targets.Clinical and experimental immunology · 2026Review
- Plasma miR-134-5p: a candidate biomarker for predicting non-response to anti-TNF therapy in rheumatoid arthritis.Frontiers in immunology · 2026Observational
- Identifying Predictive Biomarkers of Response in Patients With Rheumatoid Arthritis Treated With Adalimumab Using Machine Learning Analysis of Whole-Blood Transcriptomics Data.Arthritis & rheumatology (Hoboken, N.J.) · 2025Article
- microRNAs as Biomarkers and Therapeutic Targets in Rheumatoid Arthritis.International journal of molecular sciences · 2025Review
- A robust machine learning approach to predicting remission and stratifying risk in rheumatoid arthritis patients treated with bDMARDs.Scientific reports · 2025Article
- Artificial intelligence to predict treatment response in rheumatoid arthritis and spondyloarthritis: a scoping review.Rheumatology international · 2025Article
- Neutrophilic Activity Biomarkers (Plasma Neutrophil Extracellular Traps and Calprotectin) in Established Patients with Rheumatoid Arthritis Receiving Biological or JAK Inhibitors: A Clinical and Ultrasonographic Study.Rheumatology and therapy · 2024Article
- Towards Personalized Medicine in Rheumatoid Arthritis.Open access rheumatology : research and reviews · 2024Review
- Advancing precision rheumatology: applications of machine learning for rheumatoid arthritis management.Frontiers in immunology · 2024Review
- Comprehensive overview of microRNA function in rheumatoid arthritis.Bone research · 2023Review
- Artificial Intelligence in Rheumatoid Arthritis: Current Status and Future Perspectives: A State-of-the-Art Review.Rheumatology and therapy · 2022Review
- Machine learning-based prediction of relapse in rheumatoid arthritis patients using data on ultrasound examination and blood test.Scientific reports · 2022Article
- Estrogen receptors, ERKFrontiers in physiology · 2022Article
- Identification of SLAMF1 as an immune-related key gene associated with rheumatoid arthritis and verified in mice collagen-induced arthritis model.Frontiers in immunology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
26 authors at 7 institutions in 3 countries.
Maria Luque-TévarInstituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Hospital Reina Sofia, Universidad de Cordoba, Córdoba, Spain.
Carlos Perez-SanchezInstituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Hospital Reina Sofia, Universidad de Cordoba, Córdoba, Spain.
Alejandra Mª Patiño-TrivesInstituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Hospital Reina Sofia, Universidad de Cordoba, Córdoba, Spain.
Nuria BarbarrojaInstituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Hospital Reina Sofia, Universidad de Cordoba, Córdoba, Spain.
Ivan Arias de la RosaInstituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Hospital Reina Sofia, Universidad de Cordoba, Córdoba, Spain.
Mª Carmen Abalos-AguileraInstituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Hospital Reina Sofia, Universidad de Cordoba, Córdoba, Spain.
Juan Antonio Marin-SanzInstituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Hospital Reina Sofia, Universidad de Cordoba, Córdoba, Spain.
Desiree Ruiz-VilchezInstituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Hospital Reina Sofia, Universidad de Cordoba, Córdoba, Spain.
Rafaela Ortega-CastroInstituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Hospital Reina Sofia, Universidad de Cordoba, Córdoba, Spain.
Pilar FontInstituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Hospital Reina Sofia, Universidad de Cordoba, Córdoba, Spain.
Clementina Lopez-MedinaInstituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Hospital Reina Sofia, Universidad de Cordoba, Córdoba, Spain.
Montserrat Romero-GomezInstituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Hospital Reina Sofia, Universidad de Cordoba, Córdoba, Spain.
Carlos Rodriguez-EscaleraHospital Universitario de Jaen, Jaén, Spain.
Jose Perez-VenegasHospital Universitario Virgen Macarena, Sevilla, Spain.
Mª Dolores Ruiz-MontesinosHospital Universitario Virgen Macarena, Sevilla, Spain.
Carmen DominguezHospital Universitario Virgen Macarena, Sevilla, Spain.
Carmen Romero-BarcoHospital Clínico Universitario, Malaga, Spain.
Antonio Fernandez-NebroHospital Regional Universitario de Malaga, Malaga, Spain.
Natalia Mena-VazquezHospital Regional Universitario de Malaga, Malaga, Spain.
Jose Luis MarencoHospital Universitario Virgen de Valme, Sevilla, Spain.
Julia Uceda-MontañezHospital Universitario Virgen de Valme, Sevilla, Spain.
Mª Dolores Toledo-CoelloHospital Universitario de Jerez de la Frontera, Cádiz, Spain.
M Angeles AguirreInstituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Hospital Reina Sofia, Universidad de Cordoba, Córdoba, Spain.
Alejandro Escudero-ContrerasInstituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Hospital Reina Sofia, Universidad de Cordoba, Córdoba, Spain.
Eduardo Collantes-EstevezInstituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Hospital Reina Sofia, Universidad de Cordoba, Córdoba, Spain.
Chary Lopez-PedreraInstituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Hospital Reina Sofia, Universidad de Cordoba, Córdoba, Spain.
Instituto Maimónides de Investigación Biomédica de Córdoba · ESHospital Universitario Virgen Macarena · ESHospital Regional Universitario de Málaga · ESHospital Universitario de Valme · ESComplejo Hospitalario de Jaén · ESHospital Jerez Puerta del Sur · ESInserm · FR
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
AdultAntirheumatic AgentsArthritis, RheumatoidBiomarkersCluster AnalysisExtracellular TrapsFemaleHumansInflammationLongitudinal StudiesMachine LearningMaleMicroRNAsMiddle AgedOxidative StressPhenotypeAntirheumatic AgentsBiomarkersMicroRNAsTumor Necrosis Factor Inhibitorsanti-TNF agentsefficacyinflammationmachine learningmicroRNAsNEtosispredictorsrheumatoid arthritis
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.