Evidence map›Paper›PMID 33833674›Full record

ArticleFrontiers in computational neuroscience2021

Granular layEr Simulator: Design and Multi-GPU Simulation of the Cerebellar Granular Layer.

Giordana Florimbi, Emanuele Torti, Stefano Masoli, Egidio D'Angelo, Francesco Leporati

Abstract read
In one paragraph

Article in Frontiers in computational neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Giordana FlorimbiCustom Computing and Programmable Systems Laboratory, Department of Electrical, Computer and Biomedical Engineering, University of Pavia, Pavia, Italy.
Emanuele TortiCustom Computing and Programmable Systems Laboratory, Department of Electrical, Computer and Biomedical Engineering, University of Pavia, Pavia, Italy.
Stefano MasoliNeurocomputational Laboratory, Neurophysiology Unit, Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy.
Egidio D'AngeloNeurocomputational Laboratory, Neurophysiology Unit, Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy.
Francesco LeporatiCustom Computing and Programmable Systems Laboratory, Department of Electrical, Computer and Biomedical Engineering, University of Pavia, Pavia, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In modern computational modeling, neuroscientists need to reproduce long-lasting activity of large-scale networks, where neurons are described by highly complex mathematical models. These aspects strongly increase the computational load of the simulations, which can be efficiently performed by exploiting parallel systems to reduce the processing times. Graphics Processing Unit (GPU) devices meet this need providing on desktop High Performance Computing. In this work, authors describe a novel Granular layEr Simulator development implemented on a multi-GPU system capable of reconstructing the cerebellar granular layer in a 3D space and reproducing its neuronal activity. The reconstruction is characterized by a high level of novelty and realism considering axonal/dendritic field geometries, oriented in the 3D space, and following convergence/divergence rates provided in literature. Neurons are modeled using Hodgkin and Huxley representations. The network is validated by reproducing typical behaviors which are well-documented in the literature, such as the center-surround organization. The reconstruction of a network, whose volume is 600 × 150 × 1,200 μm

Indexed as

computational modelinggranular layer simulatorgraphics processing unithigh performance computingneuroscienceparallel processing

Identifiers

PMID33833674
PMCPMC8023391

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.