ArticleJournal of applied crystallography2021
Restoring structural parameters of lipid mixtures from small-angle X-ray scattering data.
Article in Journal of applied crystallography, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Encapsulants Affect Liposome Surface Interactions with Biological Systems.Small (Weinheim an der Bergstrasse, Germany) · 2025Article
- Changes of the lipid membrane structures caused by chain-length-dependent doxorubicin embedment in PEGylated liposomes.Journal of applied crystallography · 2025Article
- New features inJournal of applied crystallography · 2025Article
- Mechanics of biomimetic free-standing lipid membranes: insights into the elasticity of complex lipid compositions.RSC advances · 2024Article
- Dehydration does not affect lipid-based hydration lubrication.Nanoscale · 2022Article
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- Recent advances in structural characterization of biomacromolecules in foodsFrontiers in nutrition · 2022Review
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- Structure and Interdigitation of Chain-Asymmetric Phosphatidylcholines and Milk Sphingomyelin in the Fluid Phase.Symmetry · 2021Article
- Article
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4 authors.
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Abstract
Small-angle X-ray scattering (SAXS) is widely utilized to study soluble macromolecules, including those embedded into lipid carriers and delivery systems such as surfactant micelles, phospho-lipid vesicles and bilayered nanodiscs. To adequately describe the scattering from such systems, one needs to account for both the form factor (overall structure) and long-range-order Bragg reflections emerging from the organization of bilayers, which is a non-trivial task. Presently existing methods separate the analysis of lipid mixtures into distinct procedures using form-factor fitting and the fitting of the Bragg peak regions. This article describes a general approach for the computation and analysis of SAXS data from lipid mixtures over the entire angular range of an experiment. The approach allows one to restore the electron density of a lipid bilayer and simultaneously recover the corresponding size distribution and multilamellar organization of the vesicles. The method is implemented in a computer program,
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