Evidence map›Paper›PMID 33833578›Full record

ArticleCancer management and research2021

Value of Contrast-Enhanced Ultrasound in the Differential Diagnosis of Focal Splenic Lesions.

Rui Yang, Qiang Lu, Jinshun Xu, Jiayan Huang, Binyang Gao, Huan Zhang, Jie Zhou, Lanxin Du, Feng Yan

Open access · goldAbstract read
In one paragraph

Article in Cancer management and research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Splenic Hamartoma: A Case Report and Literature Review.The American journal of case reports · 2022
    Review
  8. Article
  9. Review
  10. Article
  11. Contrast-Enhanced Ultrasound Imaging Features of Focal Splenic Tuberculosis.Medical science monitor : international medical journal of experimental and clinical research · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Rui YangUltrasound Department, West China Hospital of Sichuan University, Chengdu, Sichuan, People's Republic of China.
Qiang LuUltrasound Department, West China Hospital of Sichuan University, Chengdu, Sichuan, People's Republic of China.
Jinshun XuUltrasound Department, West China Hospital of Sichuan University, Chengdu, Sichuan, People's Republic of China.ORCID 0000-0003-2420-2320
Jiayan HuangUltrasound Department, West China Hospital of Sichuan University, Chengdu, Sichuan, People's Republic of China.
Binyang GaoUltrasound Department, West China Hospital of Sichuan University, Chengdu, Sichuan, People's Republic of China.
Huan ZhangUltrasound Department, West China Hospital of Sichuan University, Chengdu, Sichuan, People's Republic of China.
Jie ZhouUltrasound Department, West China Hospital of Sichuan University, Chengdu, Sichuan, People's Republic of China.
Lanxin DuUltrasound Department, West China Hospital of Sichuan University, Chengdu, Sichuan, People's Republic of China.
Feng YanLaboratory of Ultrasound Imaging, West China Hospital of Sichuan University, Chengdu, Sichuan, People's Republic of China.ORCID 0000-0003-3715-7485
Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo identify and validate contrast-enhanced ultrasound (CEUS) features for differentiating malignant from benign splenic lesions. PATIENTS AND

methodsSplenic lesions in 123 patients who underwent conventional ultrasound (B-mode US) and CEUS were included in this study. Two radiologists evaluated the sonograms of B-mode and CEUS. Statistical analysis was performed to identify significant imaging predictors for splenic malignant lesions. Two other radiologists independently reviewed B-mode and CEUS sonograms and diagnosed the lesions based on proposed criteria as 1) benign, 2) probably benign, 3) probably malignant or 4) malignant. The diagnostic efficiency between B-mode US and CEUS was compared.

resultsCommon imaging findings of malignant lesions included hypoechoic, ill-defined margin, absence of cystic/necrotic portion, presence of splenomegaly on B-mode US, and hypoenhancement, rapid washout and presence of intralesional vessels on CEUS (

conclusionCEUS may provide more useful information than B-mode US and improve the diagnosis efficiency for distinguishing malignant from benign splenic lesions.

Indexed as

contrast-enhanced ultrasoundconventional ultrasoundspleensplenic diseases

Identifiers

PMID33833578
PMCPMC8021137
OpenAlexW3147341692

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.