Evidence map›Paper›PMID 33833445›Full record

ReviewNature reviews. Urology2021

Preoperative exercise interventions to optimize continence outcomes following radical prostatectomy.

Sean F Mungovan, Sigrid V Carlsson, Gregory C Gass, Petra L Graham, Jaspreet S Sandhu, Oguz Akin, Peter T Scardino, James A Eastham, Manish I Patel

Registry-linked trialOpen access · bronzeAbstract readReview
In one paragraph

Review in Nature reviews. Urology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06355076 (Comparison of New Reconstruction and Anastomosis in Robot-assisted Laparoscopic Radical Resection), which is not on this map. Cited by 46 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 3 pooled it
8.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06355076 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Comparison of New Reconstruction and Anastomosis in Robot-assisted Laparoscopic Radical Resection: a Prospective Randomized Controlled Study

TypeinterventionalSponsorQilu Hospital of Shandong UniversityRan2023 to 2026Enrolled94ConditionsProstate CancerArmsNew urethral reconstruction
3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 3 syntheses or guidelines pooled it, 88 citations in OpenAlex.

  1. The impact of prehabilitation on postoperative outcomes in patients undergoing radical prostatectomy for prostate cancer: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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  15. Association Between Preoperative Penile Circumference and Urinary Function After Robot-Assisted Radical Prostatectomy.International journal of urology : official journal of the Japanese Urological Association · 2025
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  18. [Prehabilitation and sport in oncology].Chirurgie (Heidelberg, Germany) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Sean F MungovanWestmead Private Physiotherapy Services, Westmead Private Hospital, Westmead, New South Wales, Australia. sean.mungovan@crinstitute.com.au.ORCID http://orcid.org/0000-0002-9949-2409
Sigrid V CarlssonUrology Service at the Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Gregory C GassThe Clinical Research Institute, Westmead, New South Wales, Australia.
Petra L GrahamDepartment of Mathematics and Statistics, Macquarie University, Macquarie Park, New South Wales, Australia.ORCID http://orcid.org/0000-0003-2890-2447
Jaspreet S SandhuUrology Service at the Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Oguz AkinDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.ORCID http://orcid.org/0000-0002-2041-6199
Peter T ScardinoUrology Service at the Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
James A EasthamUrology Service at the Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Manish I PatelSpecialty of Surgery, Sydney Medical School, The University of Sydney, Sydney, New South Wales, Australia.ORCID http://orcid.org/0000-0003-1409-9171
Memorial Sloan Kettering Cancer Center · USMacquarie University · AUThe University of Sydney · AUUniversity of Jamestown · USWestmead Hospital · AU

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
SPORE In Prostate CancerP50CA092629 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI David B. Solit · 2001 to 2026
$63.0M
Modeling Precision Interventions for Prostate Cancer ControlU01CA253915 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI ETZIONI, RUTH D, TSODIKOV, ALEXANDER · 2020 to 2025
$6.5M
Modeling to Improve Prostate Cancer Outcomes Across Diverse PopulationsU01CA199338 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI DE KONING, HARRY J, ETZIONI, RUTH D · 2015 to 2019
$5.2M
Improving shared decision making in cancer screeningK22CA234400 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI CARLSSON, SIGRID · 2019 to 2021
$621k
NCI NIH HHS K22 CA234400NCI NIH HHS P30 CA008748NCI NIH HHS P50 CA092629NCI NIH HHS U01 CA199338NCI NIH HHS U01 CA253915
6 · The paper itself

Abstract

Urinary incontinence is a common and predictable consequence among men with localized prostate cancer who have undergone radical prostatectomy. Despite advances in the surgical technique, urinary continence recovery time remains variable. A range of surgical and patient-related risk factors contributing to urinary incontinence after radical prostatectomy have been described, including age, BMI, membranous urethral length and urethral sphincter insufficiency. Physical activity interventions incorporating aerobic exercise, resistance training and pelvic floor muscle training programmes can positively influence the return to continence in men after radical prostatectomy. Traditional approaches to improving urinary continence after radical prostatectomy have typically focused on interventions delivered during the postoperative period (rehabilitation). However, the limited efficacy of these postoperative approaches has led to a shift from the traditional reactive model of care to more comprehensive interventions incorporating exercise-based programmes that begin in the preoperative period (prehabilitation) and continue after surgery. Comprehensive prehabilitation interventions include appropriately prescribed aerobic exercise, resistance training and specific pelvic floor muscle instruction and exercise training programmes. Transperineal ultrasonography is a non-invasive and validated method for the visualization of the action of the pelvic floor musculature, providing real-time visual biofeedback to the patient during specific pelvic floor muscle instruction and training. Importantly, the waiting time before surgery can be used for the delivery of comprehensive prehabilitation exercise-based interventions to increase patient preparedness in the lead-up to surgery and optimize continence and health-related quality-of-life outcomes following radical prostatectomy.

Indexed as

Preoperative ExerciseHumansMalePostoperative ComplicationsProstatectomyProstatic NeoplasmsTreatment OutcomeUrinary Incontinence

Identifiers

PMID33833445
PMCPMC8030653
OpenAlexW3151198671

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.