Evidence map›Paper›PMID 33833273›Full record

ArticleScientific reports2021

Low-temperature (< 200 °C) degradation of electronic nicotine delivery system liquids generates toxic aldehydes.

Nicholas R Jaegers, Wenda Hu, Thomas J Weber, Jian Zhi Hu

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 46 citations in OpenAlex.

  1. Review
  2. Article
  3. Well-Known and Novel Behavioural Risk Factors for Heart Failure.Journal of cardiovascular development and disease · 2026
    Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Cannabis concentrate vaping chemistry.Frontiers in toxicology · 2025
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Nicholas R JaegersPacific Northwest National Laboratory, Richland, WA, 99354, USA.ORCID 0000-0002-9930-7672
Wenda HuPacific Northwest National Laboratory, Richland, WA, 99354, USA.ORCID 0000-0002-9034-1209
Thomas J WeberPacific Northwest National Laboratory, Richland, WA, 99354, USA.ORCID 0000-0002-4413-1390
Jian Zhi HuPacific Northwest National Laboratory, Richland, WA, 99354, USA. jianzhi.hu@pnnl.gov.ORCID 0000-0001-8879-747X
Pacific Northwest National Laboratory · US

Funding

A State-of-Art NMR technique to Investigate Biologicals Effects of Electronic Nicotine Delivery SystemsR21ES029778 · NIEHS · BATTELLE PACIFIC NORTHWEST LABORATORIES · PI HU, JIAN ZHI · 2019 to 2020
$471k
NIEHS NIH HHS R21 ES029778
6 · The paper itself

Abstract

Electronic cigarette usage has spiked in popularity over recent years. The enhanced prevalence has consequently resulted in new health concerns associated with the use of these devices. Degradation of the liquids used in vaping have been identified as a concern due to the presence of toxic compounds such as aldehydes in the aerosols. Typically, such thermochemical conversions are reported to occur between 300 and 400 °C. Herein, the low-temperature thermal degradation of propylene glycol and glycerol constituents of e-cigarette vapors are explored for the first time by natural abundance

Indexed as

Administration, InhalationElectronic Nicotine Delivery SystemsTemperatureAldehydesHumansVapingAldehydes

Identifiers

PMID33833273
PMCPMC8032854
OpenAlexW3141568921

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.