Evidence map›Paper›PMID 33833076›Full record

ArticleJournal of the American Society of Nephrology : JASN2021

Initial Effects of COVID-19 on Patients with ESKD.

Eric D Weinhandl, James B Wetmore, Yi Peng, Jiannong Liu, David T Gilbertson, Kirsten L Johansen

Abstract read
In one paragraph

Article in Journal of the American Society of Nephrology : JASN, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Kidney involvement and anemia in COVID-19 infection.World journal of nephrology · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Peritoneal Dialysis Technique Survival: A Cohort Study.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. COVID-19 vaccination in peritoneal dialysis patients.International urology and nephrology · 2023
    Article
  14. Article
  15. Article
  16. Epidemiology of peritoneal dialysis outcomes.Nature reviews. Nephrology · 2022
    Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Eric D WeinhandlChronic Disease Research Group, Hennepin Healthcare Research Institute, Minneapolis, Minnesota.ORCID 0000-0001-8016-2015
James B WetmoreChronic Disease Research Group, Hennepin Healthcare Research Institute, Minneapolis, Minnesota.ORCID 0000-0003-1380-8597
Yi PengChronic Disease Research Group, Hennepin Healthcare Research Institute, Minneapolis, Minnesota.
Jiannong LiuChronic Disease Research Group, Hennepin Healthcare Research Institute, Minneapolis, Minnesota.
David T GilbertsonChronic Disease Research Group, Hennepin Healthcare Research Institute, Minneapolis, Minnesota.
Kirsten L JohansenChronic Disease Research Group, Hennepin Healthcare Research Institute, Minneapolis, Minnesota.ORCID 0000-0001-6421-361

Funding

MAINTENANCE AND UPDATE OF THE UNITED STATES RENAL DATA SYSTEM (USRDS)75N94019C00006 · NICHD · HENNEPIN HEALTHCARE RESEARCH INSTITUTE · PI JOHANSEN, KIRSTEN · 2019 to 2023
$9.8M
NICHD NIH HHS 75N94019C00006
6 · The paper itself

Abstract

backgroundReports from around the world have indicated a fatality rate of patients with coronavirus disease 2019 (COVID-19) in the range of 20%-30% among patients with ESKD. Population-level effects of COVID-19 on patients with ESKD in the United States are uncertain.

methodsWe identified patients with ESKD from Centers for Medicare and Medicaid Services data during epidemiologic weeks 3-27 of 2017-2020 and corresponding weeks of 2017-2019, stratifying them by kidney replacement therapy. Outcomes comprised hospitalization for COVID-19, all-cause death, and hospitalization for reasons other than COVID-19. We estimated adjusted relative rates (ARRs) of death and non-COVID-19 hospitalization during epidemiologic weeks 13-27 of 2020 (March 22 to July 4) versus corresponding weeks in 2017-2019.

resultsAmong patients on dialysis, the rate of COVID-19 hospitalization peaked between March 22 and April 25 2020. Non-Hispanic Black race and Hispanic ethnicity associated with higher rates of COVID-19 hospitalization, whereas peritoneal dialysis was associated with lower rates. During weeks 13-27, ARRs of death in 2020 versus 2017-2019 were 1.17 (95% confidence interval [95% CI], 1.16 to 1.19) and 1.30 (95% CI, 1.24 to 1.36) among patients undergoing dialysis or with a functioning transplant, respectively. Excess mortality was higher among non-Hispanic Black, Hispanic, and Asian patients. Among patients on dialysis, the rate of non-COVID-19 hospitalization during weeks 13-27 in 2020 was 17% lower versus hospitalization rates for corresponding weeks in 2017-2019.

conclusionsDuring the first half of 2020, the clinical outcomes of patients with ESKD were greatly affected by COVID-19, and racial and ethnic disparities were apparent. These findings should be considered in prioritizing administration of COVID-19 vaccination.

Indexed as

SARS-CoV-2AdolescentAdultAgedAged, 80 and overCause of DeathCOVID-19COVID-19 VaccinesEthnicityFemaleHealthcare DisparitiesHospitalizationHumansKidney Failure, ChronicKidney TransplantationMaleCOVID-19 VaccinesCOVID-19dialysishospitalizationmortalitytransplantation

Identifiers

PMID33833076
PMCPMC8259631

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.