Evidence map›Paper›PMID 33833058›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

His345 mutant of angiotensin-converting enzyme 2 (ACE2) remains enzymatically active against angiotensin II.

Pan Liu, Xinfang Xie, Li Gao, Jing Jin

Abstract readLetterComment
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Reply to Liu et al.: Specific mutations matter in specificity and catalysis in ACE2.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Pan LiuFeinberg Cardiovascular and Renal Research Institute, Department of Medicine-Nephrology and Hypertension, Northwestern University Feinberg School of Medicine, Chicago, IL 60611.ORCID 0000-0002-3066-652X
Xinfang XieFeinberg Cardiovascular and Renal Research Institute, Department of Medicine-Nephrology and Hypertension, Northwestern University Feinberg School of Medicine, Chicago, IL 60611.ORCID 0000-0002-0872-2986
Li GaoFeinberg Cardiovascular and Renal Research Institute, Department of Medicine-Nephrology and Hypertension, Northwestern University Feinberg School of Medicine, Chicago, IL 60611.ORCID 0000-0001-9111-9880
Jing JinFeinberg Cardiovascular and Renal Research Institute, Department of Medicine-Nephrology and Hypertension, Northwestern University Feinberg School of Medicine, Chicago, IL 60611 jing.jin@northwestern.edu.ORCID 0000-0001-7023-5305

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Angiotensin IIPeptide HormonesAngiotensin-Converting Enzyme 2Angiotensin IPeptidyl-Dipeptidase AAngiotensin-Converting Enzyme 2Angiotensin IAngiotensin IIPeptide HormonesPeptidyl-Dipeptidase A

Identifiers

PMID33833058
PMCPMC8053926

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.