Evidence map›Paper›PMID 33833034›Full record

ArticleThe European respiratory journal2021

Integrating haemodynamics identifies an extreme pulmonary hypertension phenotype.

William M Oldham, Edward Hess, Stephen W Waldo, Marc Humbert, Gaurav Choudhary, Bradley A Maron

Abstract readLetter
In one paragraph

Article in The European respiratory journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Pulmonary hypertension associated with left heart disease.The European respiratory journal · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

William M OldhamDivision of Pulmonary and Critical Care Medicine, Dept of Medicine, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA.ORCID 0000-0003-3029-4866
Edward HessRocky Mountain Regional VA Medical Center, Aurora, CO, USA.
Stephen W WaldoRocky Mountain Regional VA Medical Center, Aurora, CO, USA.
Marc HumbertUniversité Paris-Saclay, Inserm UMR_S 999, Service de Pneumologie, Hôpital Bicêtre (Assistance Publique-Hôpitaux de Paris), Le Kremlin-Bicêtre, France.ORCID 0000-0003-0703-2892
Gaurav ChoudharyProvidence Veterans Affairs Medical Center and Division of Cardiovascular Medicine, Warren Alpert Medical School of Brown University, Providence, RI, USA.ORCID 0000-0001-9343-5481
Bradley A MaronDivision of Cardiovascular Medicine, Dept of Medicine, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA.

Funding

Boston Biomedical Innovation CenterU54HL119145 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI GOLAN, DAVID E., LOSCALZO, JOSEPH · 2013 to 2021
$18.8M
Targeting FAK-NEDD9 protein-protein interaction to prevent focal adhesion assembly and vascular proliferation in pulmonary arterial hypertensionR01HL139613 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI Sirano Dhe-Paganon, Bradley Maron · 2018 to 2026
$4.1M
NEDD9-SMAD3, fibrinolysis, and chronic thromboembolic pulmonary hypertensionR01HL153502 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI MARON, BRADLEY · 2020 to 2023
$1.7M
Personalized protein-protein interactomes and precision medicine in pulmonary arterial hypertensionR01HL155096 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI MARON, BRADLEY · 2021 to 2024
$1.6M
Role of Endothelial Anoctamin-1 in Pulmonary Arterial HypertensionR01HL148727 · NHLBI · OCEAN STATE RESEARCH INSTITUTE, INC. · PI CHOUDHARY, GAURAV · 2019 to 2022
$1.6M
Regulation of pulmonary vascular cell redox state by L-2-hydroxyglutarateK08HL128802 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI OLDHAM, WILLIAM MICHAEL · 2016 to 2020
$862k
Network medicine, risk stratification, and pulmonary hypertensionR21HL145420 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI MARON, BRADLEY · 2019 to 2020
$287k
CSRD VA I01 CX001892NHLBI NIH HHS K08 HL128802NHLBI NIH HHS R01 HL139613NHLBI NIH HHS R01 HL148727NHLBI NIH HHS R01 HL153502NHLBI NIH HHS R01 HL155096NHLBI NIH HHS R21 HL145420NHLBI NIH HHS U54 HL119145
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Hypertension, PulmonaryExercise ToleranceHemodynamicsHumansPhenotype

Identifiers

PMID33833034
PMCPMC8529828

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.