Evidence map›Paper›PMID 33832511›Full record

SynthesisSystematic reviews2021

The incubation period during the pandemic of COVID-19: a systematic review and meta-analysis.

Wafa Dhouib, Jihen Maatoug, Imen Ayouni, Nawel Zammit, Rim Ghammem, Sihem Ben Fredj, Hassen Ghannem

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Systematic reviews, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. [Pulmonary innate immune response in Sars-cov-2 infection]Revista de la Facultad de Ciencias Medicas (Cordoba, Argentina) · 2022
    Pooled it
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. SARS-CoV-2 viral load and shedding kinetics.Nature reviews. Microbiology · 2023
    Review
  10. Possibility of the COVID-19 third wave in India: mapping from second wave to third wave.Indian journal of physics and proceedings of the Indian Association for the Cultivation of Science (2004) · 2023
    Article
  11. Review
  12. Article
  13. COVID-19 in one region of New Zealand: a descriptive epidemiological study.Australian and New Zealand journal of public health · 2022
    Article
  14. Article
  15. Article
  16. SARS-CoV-2 Risk Quantification Model and Validation Based on Large-Scale Dutch Test Events.International journal of environmental research and public health · 2022
    Article
  17. COVID-19 presenting after Elective Off-pump Coronary Artery Bypass Grafting and Lessons Learned.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2022
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Wafa DhouibDepartment of Epidemiology and Preventive Medicine, University of Sousse, Sousse, Tunisia. wafa.dhouib20@yahoo.fr.ORCID 0000-0001-8886-9824
Jihen MaatougDepartment of Epidemiology and Preventive Medicine, University of Sousse, Sousse, Tunisia.
Imen AyouniDepartment of Epidemiology and Preventive Medicine, University of Sousse, Sousse, Tunisia.
Nawel ZammitDepartment of Epidemiology and Preventive Medicine, University of Sousse, Sousse, Tunisia.
Rim GhammemDepartment of Epidemiology and Preventive Medicine, University of Sousse, Sousse, Tunisia.
Sihem Ben FredjDepartment of Epidemiology and Preventive Medicine, University of Sousse, Sousse, Tunisia.
Hassen GhannemDepartment of Epidemiology and Preventive Medicine, University of Sousse, Sousse, Tunisia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of our study was to determine through a systematic review and meta-analysis the incubation period of COVID-19. It was conducted based on the preferred reporting items for systematic reviews and meta-analyses (PRISMA). Criteria for eligibility were all published population-based primary literature in PubMed interface and the Science Direct, dealing with incubation period of COVID-19, written in English, since December 2019 to December 2020. We estimated the mean of the incubation period using meta-analysis, taking into account between-study heterogeneity, and the analysis with moderator variables.

resultsThis review included 42 studies done predominantly in China. The mean and median incubation period were of maximum 8 days and 12 days respectively. In various parametric models, the 95th percentiles were in the range 10.3-16 days. The highest 99th percentile would be as long as 20.4 days. Out of the 10 included studies in the meta-analysis, 8 were conducted in China, 1 in Singapore, and 1 in Argentina. The pooled mean incubation period was 6.2 (95% CI 5.4, 7.0) days. The heterogeneity (I

conclusionsThis work provides additional evidence of incubation period for COVID-19 and showed that it is prudent not to dismiss the possibility of incubation periods up to 14 days at this stage of the epidemic.

Indexed as

COVID-19Infectious Disease Incubation PeriodPandemicsArgentinaChinaHumansSingaporeContact tracingCoronavirusCOVID-19Infectious disease incubation period

Identifiers

PMID33832511
PMCPMC8031340

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.