Evidence map›Paper›PMID 33832509›Full record

ArticleEnvironmental health : a global access science source2021

Ambient air pollutants are associated with morning serum cortisol in overweight and obese Latino youth in Los Angeles.

C M Toledo-Corral, T L Alderete, M M Herting, R Habre, A K Peterson, F Lurmann, M I Goran, M J Weigensberg, F D Gilliland

Open access · goldAbstract read
In one paragraph

Article in Environmental health : a global access science source, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pollution, stress response, and obesity: A systematic review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2025
    Pooled it
  2. Trial
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Endocrine disrupting chemicals and the adrenal gland.Turkish journal of medical sciences · 2025
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Air Pollution: Another Threat to HDL Function.International journal of molecular sciences · 2022
    Review
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

C M Toledo-CorralDepartment of Health Sciences, California State University Northridge, 18111 Nordhoff Street, Northridge, 91330, USA. Claudia.Toledo-Corral@csun.edu.ORCID 0000-0002-1228-9070
T L AldereteDepartment of Integrative Physiology, University of Colorado at Boulder, Boulder, USA.
M M HertingDepartment of Preventive Medicine, Environmental Health Division, University of Southern California, Keck School of Medicine, Los Angeles, USA.
R HabreDepartment of Preventive Medicine, Environmental Health Division, University of Southern California, Keck School of Medicine, Los Angeles, USA.
A K PetersonDepartment of Preventive Medicine, Environmental Health Division, University of Southern California, Keck School of Medicine, Los Angeles, USA.
F LurmannSonoma Technology, Inc., Petaluma, USA.
M I GoranChildrens Hospital Los Angeles, Los Angeles, USA.
M J WeigensbergDepartment of Pediatrics, University of Southern California, Keck School of Medicine, Los Angeles, USA.
F D GillilandDepartment of Preventive Medicine, Environmental Health Division, University of Southern California, Keck School of Medicine, Los Angeles, USA.
University of Southern California · USSonoma Technology (United States) · USUniversity of Colorado Boulder · US

Funding

Translational Research Support CoreP30ES007048 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ROB S MCCONNELL · 1996 to 2026
$46.4M
TYPE 2 DIABETES IN HISPANIC ADOLESCENTSR01DK059211 · NIDDK · UNIVERSITY OF SOUTHERN CALIFORNIA · PI GORAN, MICHAEL ISAAC · 2000 to 2013
$9.2M
Project-002UL1GM118976 · NIGMS · CALIFORNIA STATE UNIVERSITY NORTHRIDGE · PI SAETERMOE, CARRIE L · 2015 to 2023
$7.8M
Southern California Children's Environmental Health Center (SC-CEHC)P01ES022845 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI MCCONNELL, ROB S · 2013 to 2018
$4.0M
Near-Roadway and Ambient Air Pollution Exposure and the Gut Microbiome: Implications for Obesity and Insulin Resistance in AdolescenceR00ES027853 · NIEHS · UNIVERSITY OF COLORADO · PI ALDERETE, TANYA LYNN · 2018 to 2020
$721k
NIDDK NIH HHS R01 DK059211NIDDK NIH HHS R01DK29511NIEHS NIH HHS P01 ES022845NIEHS NIH HHS P30 ES007048NIEHS NIH HHS R00 ES027853NIGMS NIH HHS UL1 GM118976NIH HHS RL1GM11875NIH HHS UL1GM118976
6 · The paper itself

Abstract

backgroundHypothalamic-pituitary-adrenal (HPA)-axis dysfunction has been associated with a variety of mental health and cardio-metabolic disorders. While causal models of HPA-axis dysregulation have been largely focused on either pre-existing health conditions or psychosocial stress factors, recent evidence suggests a possible role for central nervous system activation via air pollutants, such as nitrogen dioxide (NO

methodsIn this cross-sectional study, morning serum cortisol level was assessed after a supervised overnight fast in 203 overweight and obese Latino children and adolescents (female/male: 88/115; mean age: 11.1 ± 1.7 years; pre-pubertal/pubertal/post-pubertal: 85/101/17; BMI z-score: 2.1 ± 0.4). Cumulative concentrations of NO

resultsSingle and multi-pollutant models showed that higher O

conclusionsChronic ambient NO

Indexed as

AdolescentAir PollutantsChildCross-Sectional StudiesEnvironmental ExposureFastingFemaleHispanic or LatinoHumansHydrocortisoneLos AngelesMaleNitrogen DioxideOverweightOzoneParticulate MatterAir PollutantsHydrocortisoneNitrogen DioxideOzoneParticulate MatterAmbient air pollutionChildrenHispanicHPA-axisOzoneParticulate matterSerum cortisol

Identifiers

PMID33832509
PMCPMC8034084
OpenAlexW3147120261

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.