ArticleBMC veterinary research2021
Field infection of a gilt and its litter demonstrates vertical transmission and effect on reproductive failure caused by porcine circovirus type 3 (PCV3).
Article in BMC veterinary research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 35 citations in OpenAlex.
- Structural basis and immunogenic efficacy of porcine circovirus type 3 virus-like particle.Nature communications · 2026Article
- Concurrent histological lesions and molecular detection of porcine circovirus 3 in pigs with skeletal abnormalities and humpy-back posture.Veterinary pathology · 2026Article
- Review
- Rescue of naïve porcine circovirus type 3 and its pathogenesis in CD pigs.Journal of virology · 2025Article
- DEAD-box RNA helicase 10 inhibits porcine circovirus type 3 replication by interacting with the viral capsid protein and activating interferon responses.Journal of virology · 2025Article
- Longitudinal Monitoring of Mono- and Coinfections Involving Primary Porcine Reproductive Viruses (PCV2, PPV1, and PRRSV) as Well as Emerging Viruses (PCV3, PCV4, and nPPVs) in Primiparous and Multiparous Sows and Their Litters.Pathogens (Basel, Switzerland) · 2025Article
- Detection Rate of Porcine Circoviruses in Different Ages and Production Herds of Intensive Pig Farms in China.Animals : an open access journal from MDPI · 2025Article
- Evaluation of IgM, IgA, and IgG Antibody Responses Against PCV3 and PCV2 in Tissues of Aborted Fetuses from Late-Term Co-Infected Sows.Pathogens (Basel, Switzerland) · 2025Article
- Significant Detection of Porcine Circovirus 3 and Porcine Circovirus 4 in Wild Boars from Mid-Western Spain Without Apparent Sanitary Consequences.Animals : an open access journal from MDPI · 2025Article
- Infection and Coinfection of Porcine-Selected Viruses (PPV1 to PPV8, PCV2 to PCV4, and PRRSV) in Gilts and Their Associations with Reproductive Performance.Veterinary sciences · 2024Article
- First Report of Porcine Parvovirus 2 (PPV2) in Pigs from Colombia Associated with Porcine Reproductive Failure (PRF) and Porcine Respiratory Disease Complex (PRDC).Transboundary and emerging diseases · 2024Article
- A Retrospective Analysis of Porcine Circovirus Type 3 in Samples Collected from 2008 to 2021 in Mexico.Viruses · 2023Article
- A Subunit Vaccine Based on the VP2 Protein of Porcine Parvovirus 1 Induces a Strong Protective Effect in Pregnant Gilts.Vaccines · 2023Article
- Revisiting Porcine Circovirus Infection: Recent Insights and Its Significance in the Piggery Sector.Vaccines · 2023Review
- Vertical transmission of porcine circovirus-like virus P1 in BALB/c mice.BMC veterinary research · 2023Article
- Porcine circoviruses in wild boars in Nagano Prefecture, Japan.The Journal of veterinary medical science · 2023Article
- Experimental Inoculation of Porcine Circovirus 3 (PCV-3) in Pregnant Gilts Causes PCV-3-Associated Lesions in Newborn Piglets that Persist until Weaning.Transboundary and emerging diseases · 2023Article
- Pathogenicity and immune modulation of porcine circovirus 3.Frontiers in veterinary science · 2023Review
- Establishment and application of multiplex real-time PCR for simultaneous detection of four viruses associated with porcine reproductive failure.Frontiers in microbiology · 2023Article
- High Prevalence of Porcine Circovirus 3 in Hungarian Pig Herds: Results of a Systematic Sampling Protocol.Viruses · 2022Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPCV3 is a member of the Circovirus family, associated with disease and mortality in pigs. It is not clear whether PCV3 putatively causes clinical symptoms and disease. In the present case, we reported a gilt infected with PCV3 associated with reproductive failures, vertical transmission, tissue lesions, viral replication by in situ hybridization, and the hypothesis that some strains of PCV3 clade one are associated with reproductive failures at the field level. CASE PRESENTATION: In May 2019, a pig farm in Colombia reported increased reproductive failures, and the presence of PCV3 in gilts and sows was established in a single form or coinfections, mainly with PCV2 and PPV7. Ten sows with a single infection with PCV3 were found, and one gilt with a pre-farrowing serum viral load above 10
conclusionsThis report confirms that PCV3 can cause disease at the field level, and putatively, in this case, we find the generation of reproductive failures. The ability of PCV3 to cause disease as a putative pathogen may be associated with the viral load present in the pig and the strain that is affecting the farm. For this case, we found that viral loads above 10
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