Evidence map›Paper›PMID 33831678›Full record

ArticleJournal of psychiatric research2021

Childhood exposure to ambient air pollution and predicting individual risk of depression onset in UK adolescents.

Rachel M Latham, Christian Kieling, Louise Arseneault, Thiago Botter-Maio Rocha, Andrew Beddows, Sean D Beevers, Andrea Danese, Kathryn De Oliveira, Brandon A Kohrt, Terrie E Moffitt and 4 more

Abstract read
In one paragraph

Article in Journal of psychiatric research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Revisiting 'environmental effects': Directions for multidisciplinary investigations of air quality and psychopathology.Clinical psychological science : a journal of the Association for Psychological Science · 2026
    Article
  4. Review
  5. Article
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  7. Article
  8. Article
  9. Air Pollution's Hidden Toll: Links Between Ozone, Particulate Matter, and Adolescent Depression.International journal of environmental research and public health · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Association between prenatal and childhood PMEnvironmental epidemiology (Philadelphia, Pa.) · 2024
    Article
  14. Review
  15. Article
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Rachel M LathamKing's College London, Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, London, UK; ESRC Centre for Society and Mental Health, King's College London, London, UK.
Christian KielingDepartment of Psychiatry, Universidade Federal Do Rio Grande Do Sul, Porto Alegre, Brazil; Child and Adolescent Psychiatry Division, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil.
Louise ArseneaultKing's College London, Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, London, UK; ESRC Centre for Society and Mental Health, King's College London, London, UK.
Thiago Botter-Maio RochaDepartment of Psychiatry, Universidade Federal Do Rio Grande Do Sul, Porto Alegre, Brazil; Child and Adolescent Psychiatry Division, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil.
Andrew BeddowsEnvironmental Research Group, School of Public Health, Imperial College London, London, UK.
Sean D BeeversEnvironmental Research Group, School of Public Health, Imperial College London, London, UK.
Andrea DaneseKing's College London, Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, London, UK; King's College London, Department of Child and Adolescent Psychiatry, Institute of Psychiatry, Psychology and Neuroscience, London, UK; National and Specialist CAMHS Trauma, Anxiety, and Depression Clinic, South London and Maudsley NHS Foundation Trust, London, UK.
Kathryn De OliveiraKing's College London, Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, London, UK.
Brandon A KohrtDivision of Global Mental Health, George Washington University, Washington, DC, USA.
Terrie E MoffittKing's College London, Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, London, UK; Department of Psychology and Neuroscience, Duke University, Durham, NC, USA; Psychiatry and Behavioral Sciences, Duke University, Durham, NC, USA; Center for Genomic and Computational Biology, Duke University, Durham, NC, USA; PROMENTA, Department of Psychology, University of Oslo, Norway.
Valeria MondelliKing's College London, Department of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Joanne B NewburyBristol Medical School: Population and Health Sciences, University of Bristol, Bristol, UK.
Aaron ReubenDepartment of Psychology and Neuroscience, Duke University, Durham, NC, USA.
Helen L FisherKing's College London, Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, London, UK; ESRC Centre for Society and Mental Health, King's College London, London, UK. Electronic address: helen.2.fisher@kcl.ac.uk.

Funding

RESHAPE Diversity SupplementR01MH120649 · NIMH · GEORGE WASHINGTON UNIVERSITY · PI KOHRT, BRANDON ALAN · 2019 to 2023
$3.5M
Neuropsychological and genomic signatures of violence exposure in childhoodR01HD077482 · NICHD · DUKE UNIVERSITY · PI CASPI, AVSHALOM · 2013 to 2018
$2.8M
Evaluating neurodegenerative risk in middle-aged adults exposed to lead as childrenF31ES029358 · NIEHS · DUKE UNIVERSITY · PI REUBEN, AARON · 2018 to 2020
$113k
Medical Research Council G1002190Medical Research Council MC_PC_MR/R019460/1Medical Research Council MR/S019669/1NICHD NIH HHS R01 HD077482NIEHS NIH HHS F31 ES029358NIMH NIH HHS R01 MH120649Wellcome TrustWellcome Trust 218632/Z/19/Z
6 · The paper itself

Abstract

Knowledge about early risk factors for major depressive disorder (MDD) is critical to identify those who are at high risk. A multivariable model to predict adolescents' individual risk of future MDD has recently been developed however its performance in a UK sample was far from perfect. Given the potential role of air pollution in the aetiology of depression, we investigate whether including childhood exposure to air pollution as an additional predictor in the risk prediction model improves the identification of UK adolescents who are at greatest risk for developing MDD. We used data from the Environmental Risk (E-Risk) Longitudinal Twin Study, a nationally representative UK birth cohort of 2232 children followed to age 18 with 93% retention. Annual exposure to four pollutants - nitrogen dioxide (NO

Indexed as

Air PollutantsAir PollutionMajor Depressive DisorderAdolescentChildDepressionEnvironmental ExposureHumansUnited KingdomAir PollutantsEnvironmentMental healthNet reclassification improvementPrediction modelPsychopathologyRisk calculator

Identifiers

PMID33831678
PMCPMC8412033

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.