Evidence map›Paper›PMID 33831594›Full record

ArticleMedical image analysis2021

Deep neural network ensemble for on-the-fly quality control-driven segmentation of cardiac MRI T1 mapping.

Evan Hann, Iulia A Popescu, Qiang Zhang, Ricardo A Gonzales, Ahmet Barutçu, Stefan Neubauer, Vanessa M Ferreira, Stefan K Piechnik

Open access · hybridAbstract read
In one paragraph

Article in Medical image analysis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
8.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 77 citations in OpenAlex.

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  15. Improved robustness for deep learning-based segmentation of multi-center myocardial perfusion cardiovascular MRI datasets using data-adaptive uncertainty-guided space-time analysis.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2024
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  19. Temporal Uncertainty Localization to Enable Human-in-the-Loop Analysis of Dynamic Contrast-Enhanced Cardiac MRI Datasets.Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Evan HannOxford University Centre for Clinical Magnetic Resonance Research (OCMR), Level 0, John Radcliffe Hospital, Headington, Oxford OX3 9DU, United Kingdom. Electronic address: evan.hann@cardiov.ox.ac.uk.
Iulia A PopescuOxford University Centre for Clinical Magnetic Resonance Research (OCMR), Level 0, John Radcliffe Hospital, Headington, Oxford OX3 9DU, United Kingdom.
Qiang ZhangOxford University Centre for Clinical Magnetic Resonance Research (OCMR), Level 0, John Radcliffe Hospital, Headington, Oxford OX3 9DU, United Kingdom.
Ricardo A GonzalesOxford University Centre for Clinical Magnetic Resonance Research (OCMR), Level 0, John Radcliffe Hospital, Headington, Oxford OX3 9DU, United Kingdom.
Ahmet BarutçuOxford University Centre for Clinical Magnetic Resonance Research (OCMR), Level 0, John Radcliffe Hospital, Headington, Oxford OX3 9DU, United Kingdom; Çanakkale Onsekiz Mart University, Barbaros, 17100 Kepez/Çanakkale Merkez/Çanakkale, Turkey.
Stefan NeubauerOxford University Centre for Clinical Magnetic Resonance Research (OCMR), Level 0, John Radcliffe Hospital, Headington, Oxford OX3 9DU, United Kingdom.
Vanessa M FerreiraOxford University Centre for Clinical Magnetic Resonance Research (OCMR), Level 0, John Radcliffe Hospital, Headington, Oxford OX3 9DU, United Kingdom.
Stefan K PiechnikOxford University Centre for Clinical Magnetic Resonance Research (OCMR), Level 0, John Radcliffe Hospital, Headington, Oxford OX3 9DU, United Kingdom.
John Radcliffe Hospital · GBÇanakkale Onsekiz Mart Üniversitesi · TR

Funding

British Heart Foundation PG/15/71/31731Department of Health
6 · The paper itself

Abstract

Recent developments in artificial intelligence have generated increasing interest to deploy automated image analysis for diagnostic imaging and large-scale clinical applications. However, inaccuracy from automated methods could lead to incorrect conclusions, diagnoses or even harm to patients. Manual inspection for potential inaccuracies is labor-intensive and time-consuming, hampering progress towards fast and accurate clinical reporting in high volumes. To promote reliable fully-automated image analysis, we propose a quality control-driven (QCD) segmentation framework. It is an ensemble of neural networks that integrate image analysis and quality control. The novelty of this framework is the selection of the most optimal segmentation based on predicted segmentation accuracy, on-the-fly. Additionally, this framework visualizes segmentation agreement to provide traceability of the quality control process. In this work, we demonstrated the utility of the framework in cardiovascular magnetic resonance T1-mapping - a quantitative technique for myocardial tissue characterization. The framework achieved near-perfect agreement with expert image analysts in estimating myocardial T1 value (r=0.987,p<.0005; mean absolute error (MAE)=11.3ms), with accurate segmentation quality prediction (Dice coefficient prediction MAE=0.0339) and classification (accuracy=0.99), and a fast average processing time of 0.39 second/image. In summary, the QCD framework can generate high-throughput automated image analysis with speed and accuracy that is highly desirable for large-scale clinical applications.

Indexed as

Artificial IntelligenceMagnetic Resonance ImagingHumansImage Processing, Computer-AssistedNeural Networks, ComputerQuality ControlReproducibility of ResultsCardiovascular MRIEnsemble neural networkImage quality assessmentSegmentation

Identifiers

PMID33831594
PMCPMC8204226
OpenAlexW3138480930

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.