Evidence map›Paper›PMID 33831187›Full record

Observational studyEuropean heart journal. Quality of care & clinical outcomes2022

Causes, pattern, predictors, and prognostic implications of new hospitalizations after transcatheter aortic valve implantation: a long-term nationwide observational study.

Konrad Nilsson, Sergio Buccheri, Christina Christersson, Sasha Koul, Johan Nilsson, Pétur Pétursson, Henrik Renlund, Andreas Rück, Stefan James

Open access · hybridAbstract readObservational Study
In one paragraph

Observational study in European heart journal. Quality of care & clinical outcomes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Konrad NilssonDepartment of Medical Sciences, Uppsala University, Uppsala University Hospital, Ing. 40, 751 85 Uppsala, Sweden.ORCID 0000-0002-8329-5072
Sergio BuccheriDepartment of Medical Sciences, Uppsala University, Uppsala University Hospital, Ing. 40, 751 85 Uppsala, Sweden.ORCID 0000-0002-7767-3073
Christina ChristerssonDepartment of Medical Sciences, Uppsala University, Uppsala University Hospital, Ing. 40, 751 85 Uppsala, Sweden.
Sasha KoulDepartment of Cardiology, Lund University, 221 84 Lund, Sweden.
Johan NilssonDepartment of Public Health and Clinical Medicine, Umea University, 901 87 Umea, Sweden.
Pétur PéturssonDepartment of Cardiology, Sahlgrenska University Hospital, 413 45 Gothenburg, Sweden.
Henrik RenlundUppsala Clinical Research Center, Uppsala Science Park, Hubben, Dag Hammarskjölds väg 38, 751 85 Uppsala, Sweden.ORCID 0000-0002-2141-6086
Andreas RückDepartment of Cardiology, Karolinska Institute, 171 77 Stockholm, Sweden.
Stefan JamesDepartment of Medical Sciences, Uppsala University, Uppsala University Hospital, Ing. 40, 751 85 Uppsala, Sweden.
Uppsala University · SEUppsala University Hospital · SEKarolinska Institutet · SELund University · SESahlgrenska University Hospital · SEUmeå University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThe aim of this study was to investigate the pattern, causes, and predictors of all new hospitalizations in patients who underwent transcatheter aortic valve implantation (TAVI). METHODS AND

resultsThe nationwide Swedish TAVI registry was merged with other mandatory healthcare registries, which enabled the analysis of all TAVI procedures, new hospital admissions, and death between the years 2008 and 2017. A total of 2821 patients underwent TAVI with a mean of 2.5 hospitalizations during a mean follow-up of 2.2 years. Hospitalizations were associated with worse prognosis. Heart failure (HF) was the most common cause of hospitalization with 19% having at least one hospitalization due to HF causing, 16% of all-cause admissions, and 50% of cardiovascular admissions. Male gender, age >90 years, high Charlson Comorbidity Index, atrial fibrillation, present neurologic disease, severe renal impairment, peripheral vascular disease, New York Heart Association class IV, mild or moderate mean aortic valve gradients, and pulmonary hypertension were associated with an increased risk for all-cause hospitalizations or death. For cardiovascular hospitalization or death, the pattern was similar, with the addition of impaired systolic left ventricular function as a predictor.

conclusionMultiple hospitalizations after TAVI are common and are often caused by HF. Reducing the rate of HF hospitalizations is important to mitigate the burden on the healthcare system due to new hospitalizations after TAVI.

Indexed as

Aortic Valve StenosisTranscatheter Aortic Valve ReplacementAged, 80 and overFemaleHospitalizationHumansMalePrognosisRisk FactorsTreatment OutcomeHeart failureHospitalizationRepeated eventsTAVI

Identifiers

PMID33831187
PMCPMC8888128
OpenAlexW3140225614

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.