ArticlePloS one2021
Aetiology of acute diarrhoea in children in Shanghai, 2015-2018.
Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
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Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.
- Epidemiological characteristics of rotavirus gastroenteritis in China: A systematic review of studies published from 2014 to 2023.Human vaccines & immunotherapeutics · 2026Pooled it
- Human adenoviruses in children with gastroenteritis: a systematic review and meta-analysis.BMC infectious diseases · 2024Pooled it
- Chronic exposure to intestinal parasites and bacterial enteropathogens among children in rural Madagascar: Implications for asymptomatic carriage and co-infections.PLoS neglected tropical diseases · 2026Article
- [Antimicrobial resistance characteristics ofZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2026Article
- Epidemiology and Antibiotic Resistance of Foodborne Diseases Among Children in Shanghai: A Four-Year Surveillance Study, 2021-2024.Infection and drug resistance · 2026Article
- Virulence characteristics and antibiotic resistance analysis of multi-drug resistant Enterotoxigenic Escherichia coli in healthy pigs from Zhejiang Province, China.BMC veterinary research · 2025Article
- Review
- High Efficacy of Rose Bengal in Reducing the Pathogenicity ofInternational journal of microbiology · 2025Article
- Probiotics for treating acute diarrhea in children: an evidence synthesis.Frontiers in pediatrics · 2025Review
- The burden and etiologies of diarrhea in Asia and its countries from 1990 to 2021 and the forecast to 2040: analyses informed by the global burden of disease study 2021.Frontiers in public health · 2025Article
- Surveillance of Pathogens Causing Viral Diarrhea in Yichang in 2022 and 2023.Intervirology · 2025Article
- Analysis and application of volatile metabolic profiles ofRSC advances · 2024Article
- Article
- Prevalence and genetic characterization of viral gastroenteritis in hospitalized children aged <5 years in Yunnan Province, China, 2020-2022.Frontiers in pediatrics · 2024Article
- Etiological surveillance of viral diarrhea from 2017 to 2019 in Zhangzhou city, Fujian province, China.Frontiers in public health · 2024Article
- Effects of Ambient Temperature, Relative Humidity, and Precipitation on Diarrhea Incidence in Surabaya.International journal of environmental research and public health · 2023Article
- Quantifying the effects of anomalies of temperature, precipitation, and surface water storage on diarrhea risk in Taiwan.Epidemiology and health · 2023Article
- Virological and Epidemiological Features of Norovirus Infections in Brazil, 2017-2018.Viruses · 2021Article
- Antibiotic Prescription Patterns in Children Under 5 Years of Age With Acute Diarrhea in Quito-Ecuador.Journal of primary care & community healthArticle
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Diarrhoea remains a major cause of childhood morbidity and mortality worldwide. This study aimed to monitor the aetiology of acute diarrhoea in children in Shanghai. Paediatric outpatients with acute diarrhoea were enrolled in the study from Jan 2015 to Dec 2018. Faecal samples were collected for testing. Enteric bacteria were identified and typed by culture and serotyping, respectively. Enteric viruses were identified by real-time PCR. Enteric pathogens were identified in 1572 (58.4%) of the 2692 enrolled children with acute diarrhoea. Viruses were detected more frequently than bacteria (41.3% versus 25.0%). Nontyphoidal Salmonella spp. (NTS) was the most common (10.3%) bacteria isolated, followed by enteropathogenic Escherichia coli (EPEC) (6.5%), enteroaggregative Escherichia coli (EAEC) (6.2%), Campylobacter spp. (3.6%), enterotoxigenic Escherichia coli (ETEC) (1.1%), Shigella spp. (0.2%), and enterohemorrhagic Escherichia coli (EHEC) (0.1%). Rotavirus was the most common (16.0%) virus detected, followed by norovirus (15.5%), adenovirus (7.2%), sapovirus (3.0%) and astrovirus (2.7%). Rotavirus, norovirus and NTS were the major pathogens responsible for diarrhoea in Shanghainese children. Improving uptake of the rotavirus vaccine and strengthening foodborne-pathogen prevention will aid in reducing the burden of diarrhoeal disease in children in Shanghai.
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