Evidence map›Paper›PMID 33831095›Full record

ArticlePloS one2021

Active screening of patients with diabetes mellitus for pulmonary tuberculosis in a tertiary care hospital in Sri Lanka.

Sumudu Hewage, Noel Somasundaram, Vithiya Ratnasamy, Ishara Ranathunga, Amitha Fernando, Indika Perera, Udara Perera, Dhammika Vidanagama, Mizaya Cader, Poorna Fernando and 5 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Development and validation of the Tuberculosis Diabetes Mellitus-Predictive Tool (TBDM-PT) in primary care.Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia · 2025
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Sumudu HewageNational Program for Tuberculosis Control and Chest Diseases, Ministry of Health, Colombo, Sri Lanka.ORCID 0000-0001-8079-4338
Noel SomasundaramDiabetes and Endocrinology Unit, National Hospital of Sri Lanka, Colombo, Sri Lanka.
Vithiya RatnasamyDiabetes and Endocrinology Unit, National Hospital of Sri Lanka, Colombo, Sri Lanka.
Ishara RanathungaDiabetes and Endocrinology Unit, National Hospital of Sri Lanka, Colombo, Sri Lanka.ORCID 0000-0002-2188-5309
Amitha FernandoNational Program for Tuberculosis Control and Chest Diseases, Ministry of Health, Colombo, Sri Lanka.
Indika PereraCentral Chest Clinic, Colombo, Sri Lanka.
Udara PereraHealth Informatics Unit, Ministry of Health, Colombo, Sri Lanka.
Dhammika VidanagamaMicrobiology Department, National Hospital of Sri Lanka, Colombo, Sri Lanka.
Mizaya CaderNational Program for Tuberculosis Control and Chest Diseases, Ministry of Health, Colombo, Sri Lanka.
Poorna FernandoHealth Informatics Unit, Ministry of Health, Colombo, Sri Lanka.
Nirupa PallewatteNational Program for Tuberculosis Control and Chest Diseases, Ministry of Health, Colombo, Sri Lanka.
Lakmal RathnayakaNational Program for Tuberculosis Control and Chest Diseases, Ministry of Health, Colombo, Sri Lanka.
Dushani JayawardhanaNational Program for Tuberculosis Control and Chest Diseases, Ministry of Health, Colombo, Sri Lanka.
Manjula DanansuriyaWorld Health Organization Country Office for Sri Lanka, Colombo, Sri Lanka.
Nalika GunawardenaWorld Health Organization Country Office for Sri Lanka, Colombo, Sri Lanka.
National Hospital of Sri Lanka · LKMinistry of Health, Nutrition and Indigenous Medicine · LK

Funding

World Health Organization 001
6 · The paper itself

Abstract

End TB strategy by the WHO suggest active screening of high-risk populations for tuberculosis (TB) to improve case detection. Present study generates evidence for the effectiveness of screening patients with diabetes mellitus (DM) for Pulmonary TB (PTB). A study was conducted among 4548 systematically recruited patients over 45 years attending DM clinic at the National Hospital of Sri Lanka. The study units followed an algorithm specifying TB symptom and risk factor screening for all, followed by investigations and clinical assessments for those indicated. Bacteriologically confirmed or clinically diagnosed PTB were presented as proportions with 95% CI. Mean (SD) age was 62·5 (29·1) years. Among patients who completed all indicated steps of algorithm, 3500 (76·9%) were investigated and 127 (2·8%) underwent clinical assessment. Proportion of bacteriologically confirmed PTB patients was 0·1% (n = 6,95%CI = 0·0-0·3%). None were detected clinically. Analysis revealed PTB detection rates among males aged ≥60 years with HbA1c ≥ 8 to be 0·4% (n = 2, 95%CI = 0·0-1·4%). The study concludes that active screening for PTB among all DM patients at clinic settings in Sri Lanka, to be non-effective measure to enhance TB case finding. However, the sub-category of diabetic males with uncontrolled diabetics who are over 60 years of age is recommended as an option to consider for active screening for PTB.

Indexed as

AgedCross-Sectional StudiesDiabetes MellitusFemaleHumansMaleMass ScreeningMiddle AgedRisk FactorsSri LankaTertiary Care CentersTuberculosis, Pulmonary

Identifiers

PMID33831095
PMCPMC8031956
OpenAlexW3146532421

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.