Evidence map›Paper›PMID 33830710›Full record

ArticleThe New England journal of medicine2021

Vancomycin Infusion Reaction - Moving beyond "Red Man Syndrome".

Santiago Alvarez-Arango, S Michelle Ogunwole, Thomas D Sequist, Caitlin M Burk, Kimberly G Blumenthal

Abstract read
In one paragraph

Article in The New England journal of medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Oritavancin safety: a real-world pharmacovigilance study of the FAERS database.Frontiers in cellular and infection microbiology · 2026
    Article
  5. Article
  6. Article
  7. Documentation of DRESS in the allergy list of patients with a prior history of DRESS.The journal of allergy and clinical immunology. In practice · 2025
    Article
  8. Article
  9. A Skin Testing Strategy for Non-IgE-Mediated Reactions Associated With Vancomycin.The journal of allergy and clinical immunology. In practice · 2024
    Article
  10. Article
  11. Non-IgE-Mediated Immediate Drug-Induced Hypersensitivity Reactions.The journal of allergy and clinical immunology. In practice · 2024
    Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Santiago Alvarez-ArangoFrom the Divisions of Allergy and Clinical Immunology and of Clinical Pharmacology (S.A.A.) and the Department of Medicine (S.M.O.), Johns Hopkins University, and the Johns Hopkins Center for Health Equity (S.M.O.) - both in Baltimore; and the Department of Medicine, Brigham and Women's Hospital (T.D.S.), Harvard Medical School (T.D.S., K.G.B.), and the Division of Rheumatology, Allergy, and Immunology (C.M.B., K.G.B.), and the Edward P. Lawrence Center for Quality and Safety (K.G.B.), Massachusetts General Hospital - all in Boston.ORCID 0000-0002-4110-7221
S Michelle OgunwoleFrom the Divisions of Allergy and Clinical Immunology and of Clinical Pharmacology (S.A.A.) and the Department of Medicine (S.M.O.), Johns Hopkins University, and the Johns Hopkins Center for Health Equity (S.M.O.) - both in Baltimore; and the Department of Medicine, Brigham and Women's Hospital (T.D.S.), Harvard Medical School (T.D.S., K.G.B.), and the Division of Rheumatology, Allergy, and Immunology (C.M.B., K.G.B.), and the Edward P. Lawrence Center for Quality and Safety (K.G.B.), Massachusetts General Hospital - all in Boston.ORCID 0000-0001-9479-7695
Thomas D SequistFrom the Divisions of Allergy and Clinical Immunology and of Clinical Pharmacology (S.A.A.) and the Department of Medicine (S.M.O.), Johns Hopkins University, and the Johns Hopkins Center for Health Equity (S.M.O.) - both in Baltimore; and the Department of Medicine, Brigham and Women's Hospital (T.D.S.), Harvard Medical School (T.D.S., K.G.B.), and the Division of Rheumatology, Allergy, and Immunology (C.M.B., K.G.B.), and the Edward P. Lawrence Center for Quality and Safety (K.G.B.), Massachusetts General Hospital - all in Boston.
Caitlin M BurkFrom the Divisions of Allergy and Clinical Immunology and of Clinical Pharmacology (S.A.A.) and the Department of Medicine (S.M.O.), Johns Hopkins University, and the Johns Hopkins Center for Health Equity (S.M.O.) - both in Baltimore; and the Department of Medicine, Brigham and Women's Hospital (T.D.S.), Harvard Medical School (T.D.S., K.G.B.), and the Division of Rheumatology, Allergy, and Immunology (C.M.B., K.G.B.), and the Edward P. Lawrence Center for Quality and Safety (K.G.B.), Massachusetts General Hospital - all in Boston.
Kimberly G BlumenthalFrom the Divisions of Allergy and Clinical Immunology and of Clinical Pharmacology (S.A.A.) and the Department of Medicine (S.M.O.), Johns Hopkins University, and the Johns Hopkins Center for Health Equity (S.M.O.) - both in Baltimore; and the Department of Medicine, Brigham and Women's Hospital (T.D.S.), Harvard Medical School (T.D.S., K.G.B.), and the Division of Rheumatology, Allergy, and Immunology (C.M.B., K.G.B.), and the Edward P. Lawrence Center for Quality and Safety (K.G.B.), Massachusetts General Hospital - all in Boston.

Funding

Clinical Pharmacology Training ProgramT32GM066691 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI Matthew Michael Ippolito · 2003 to 2026
$6.4M
The Clinical and Economic Impact of Penicillin AllergyK01AI125631 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI BLUMENTHAL, KIMBERLY GOLD · 2016 to 2021
$779k
NIAID NIH HHS K01 AI125631NIGMS NIH HHS T32 GM066691
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Drug HypersensitivityElectronic Health RecordsTerminology as TopicAnti-Bacterial AgentsEducation, MedicalErythemaFemaleHumansInfusions, IntravenousMaleNatural Language ProcessingRacismSyndromeVancomycinAnti-Bacterial AgentsVancomycin

Identifiers

PMID33830710
PMCPMC9235042

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.