Evidence map›Paper›PMID 33830641›Full record

ArticleThe FEBS journal2021

Influenza A virus infection-induced macroautophagy facilitates MHC class II-restricted endogenous presentation of an immunodominant viral epitope.

Jieru Deng, Chunni Lu, Chuanxin Liu, Sara Oveissi, W Douglas Fairlie, Erinna F Lee, Pamuk Bilsel, Hamsa Puthalakath, Weisan Chen

Open access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in The FEBS journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Jieru DengDepartment of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, Bundoora, Vic., Australia.
Chunni LuDepartment of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, Bundoora, Vic., Australia.
Chuanxin LiuDepartment of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, Bundoora, Vic., Australia.
Sara OveissiDepartment of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, Bundoora, Vic., Australia.
W Douglas FairlieDepartment of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, Bundoora, Vic., Australia.
Erinna F LeeDepartment of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, Bundoora, Vic., Australia.
Pamuk BilselFluGen Inc., Madison, WI, USA.
Hamsa PuthalakathDepartment of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, Bundoora, Vic., Australia.ORCID 0000-0001-5178-1175
Weisan ChenDepartment of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, Bundoora, Vic., Australia.ORCID 0000-0002-5221-9771
La Trobe University · AUDeakin University · AUFluGen (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CD4

Indexed as

AnimalsAntigen PresentationAntigens, ViralAutophagy-Related Protein 7Beclin-1Bone Marrow CellsBrefeldin ACD4-Positive T-LymphocytesDendritic CellsFemaleGene ExpressionHEK293 CellsHistocompatibility Antigens Class IIHost-Pathogen InteractionsHumansImmunodominant EpitopesAntigens, ViralAtg7 protein, mouseAutophagy-Related Protein 7Beclin-1Brefeldin AHistocompatibility Antigens Class IIImmunodominant Epitopesantigen presentationCD4+ T cellinfluenza A virusmacroautophagyMHC-II

Identifiers

PMID33830641
OpenAlexW3111447485

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.