ArticleEnvironmental microbiology2021
Temperature regulation of membrane composition in the Firmicute, Enterococcus faecalis, parallels that of Escherichia coli.
Article in Environmental microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Monounsaturated fatty acid biosynthesis is critical for streptococcal envelope homeostasis and stress tolerance.Journal of bacteriology · 2026Article
- Diverse unsaturated fatty acids bypass loss of FabH-catalysed initiation of fatty acid synthesis inMicrobiology (Reading, England) · 2026Article
- The MarR family regulator RmaH underlies the trade-off between acid sensitivity and antibiotic tolerance inJournal of bacteriology · 2026Article
- Monounsaturated fatty acid biosynthesis is critical for streptococcal envelope homeostasis and stress tolerance.bioRxiv : the preprint server for biology · 2026Article
- Appraisal of biohydrogenating probiotic enzymes for the synthesis of conjugated linoleic acid isomers.Frontiers in microbiology · 2026Review
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- Not too rigid nor too wobbly: Defining an optimal membrane fluidity range essential for biofilm formation inmLife · 2025Article
- Fatty acid synthesis and utilization in gram-positive bacteria: insights fromMicrobiology and molecular biology reviews : MMBR · 2025Review
- Unsaturated fatty acid synthesis in bacteria: Mechanisms and regulation of canonical and remarkably noncanonical pathways.Biochimie · 2024Review
- Antibacterial Property and Mechanisms of Au@Ag Core-Shell Nanoparticles with Near-Infrared Absorption AgainstInternational journal of nanomedicine · 2024Article
- Comprehensive phenomic and genomic studies of the species,Frontiers in plant science · 2024Article
- Variations in the Intestinal Microbiota of the Chinese Soft-Shelled Turtle (Animals : an open access journal from MDPI · 2023Article
- Unsaturated fatty acid synthesis in Enterococcus faecalis requires a specific enoyl-ACP reductase.Molecular microbiology · 2022Article
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- Phosphate Ions Alter the Binding of Daptomycin to Living Bacterial Cell Surfaces.ACS infectious diseases · 2021Article
- Structure and mechanistic analyses of the gating mechanism of elongating ketosynthases.ACS catalysis · 2021Article
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Abstract
Both Enterococcus faecalis and Escherichia coli can undergo abrupt temperature transitions in nature. E. coli changes the composition of its phospholipid acyl chains in response to shifts growth temperature. This is mediated by a naturally temperature sensitive enzyme, FabF (3-ketoacyl-acyl carrier protein synthase II), that elongates the 16 carbon unsaturated acyl chain palmitoleate to the 18 carbon unsaturated acyl chain, cis-vaccenate. FabF is more active at low temperatures resulting in increased incorporation of cis-vaccenoyl acyl chains into the membrane phospholipids. This response to temperature is an intrinsic property of FabF and does not require increased synthesis of the enzyme. We report that the FabF of the very divergent bacterium, E. faecalis, has properties very similar to E. coli FabF and is responsible for changing E. faecalis membrane phospholipid acyl chain composition in response to temperature. Moreover, expression E. faecalis FabF in an E. coli ∆fabF strain restores temperature regulation to the E. coli strain.
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