Evidence map›Paper›PMID 33830291›Full record

ArticlePediatric radiology2021

Free-breathing radial stack-of-stars three-dimensional Dixon gradient echo sequence in abdominal magnetic resonance imaging in sedated pediatric patients.

Patrick B Duffy, Alto Stemmer, Michael J Callahan, Joseph P Cravero, Patrick R Johnston, Simon K Warfield, Sarah D Bixby

Abstract read
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In one paragraph

Article in Pediatric radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Patrick B DuffyDepartment of Radiology, Boston Children's Hospital, 300 Longwood Ave., Boston, MA, 02115, USA.
Alto StemmerSiemens Healthineers, Erlangen, Germany.
Michael J CallahanDepartment of Radiology, Boston Children's Hospital, 300 Longwood Ave., Boston, MA, 02115, USA.
Joseph P CraveroDepartment of Anesthesiology, Boston Children's Hospital, Boston, MA, USA.
Patrick R JohnstonDepartment of Radiology, Boston Children's Hospital, 300 Longwood Ave., Boston, MA, 02115, USA.
Simon K WarfieldDepartment of Radiology, Boston Children's Hospital, 300 Longwood Ave., Boston, MA, 02115, USA.
Sarah D BixbyDepartment of Radiology, Boston Children's Hospital, 300 Longwood Ave., Boston, MA, 02115, USA. sarah.bixby@childrens.harvard.edu.ORCID http://orcid.org/0000-0002-6271-6085
Boston Children's Hospital · USSiemens Healthineers (Germany) · DE

Funding

Improved Motion Robust MRI of ChildrenR01EB019483 · NIBIB · BOSTON CHILDREN'S HOSPITAL · PI WARFIELD, SIMON K · 2015 to 2024
$3.9M
NIBIB NIH HHS R01EB019483
6 · The paper itself

Abstract

backgroundThere is a strong need for improvements in motion robust T1-weighted abdominal imaging sequences in children to enable high-quality, free-breathing imaging.

objectiveTo compare imaging time and quality of a radial stack-of-stars, free-breathing T1-weighted gradient echo acquisition (volumetric interpolated breath-hold examination [VIBE]) three-dimensional (3-D) Dixon sequence in sedated pediatric patients undergoing abdominal magnetic resonance imaging (MRI) against conventional Cartesian T1-weighed sequences. MATERIALS AND

methodsThis study was approved by the institutional review board with informed consent obtained from all subjects. Study subjects included 31 pediatric patients (19 male, 12 female; median age: 5 years; interquartile range: 5 years) undergoing abdominal MRI at 3 tesla with a free-breathing T1-weighted radial stack-of-stars 3-D VIBE Dixon prototype sequence, StarVIBE Dixon (radial technique), between October 2018 and June 2019 with previous abdominal MR imaging using conventional Cartesian T1-weighed imaging (traditional technique). MRI component times were recorded as well as the total number of non-contrast T1-weighted sequences. Two radiologists independently rated images for quality using a scale from 1 to 5 according to the following metrics: overall image quality, hepatic edge sharpness, hepatic vessel clarity and respiratory motion robustness. Scores were compared between the groups.

resultsMean T1-weighted imaging times for all subjects were 3.63 min for radial exams and 8.01 min for traditional exams (P<0.001), and total non-contrast imaging time was 32.7 min vs. 43.9 min (P=0.002). Adjusted mean total MRI time for all subjects was 60.2 min for radial exams and 65.7 min for traditional exams (P=0.387). The mean number of non-contrast T1-weighted sequences performed in radial MRI exams was 1.0 compared to 1.9 (range: 0-6) in traditional exams (P<0.001). StarVIBE Dixon outperformed Cartesian methods in all quality metrics. The mean overall image quality (scale 1-5) was 3.95 for radial exams and 3.31 for traditional exams (P<0.001).

conclusionRadial stack-of-stars 3-D VIBE Dixon during free-breathing abdominal MRI in pediatric patients offers improved image quality compared to Cartesian T1-weighted imaging techniques with decreased T1-weighted and total non-contrast imaging time. This has important implications for children undergoing sedation for imaging.

Indexed as

Imaging, Three-DimensionalMagnetic Resonance ImagingAbdomenArtifactsChildChild, PreschoolContrast MediaFemaleHumansImage EnhancementMaleMotionRespirationContrast MediaAbdomenChildrenFree-breathingMagnetic resonance imagingRadialSedationT1-weighted

Identifiers

PMID33830291
OpenAlexW3147677534

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.